Evidence map›Paper›PMID 36990440›Full record

ArticleDeutsche medizinische Wochenschrift (1946)2023

[Enhanced targeted influenza vaccines - New evidence shows higher effectiveness in older adults].

Markus Frühwein, Jörg Schelling, Klaus Wahle, Dietmar Beier, Anja Kwetkat, Tino F Schwarz

Open access · hybridAbstract readEnglish Abstract
In one paragraph

Article in Deutsche medizinische Wochenschrift (1946), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Markus FrühweinDr. Frühwein & Partner - Praxis für Allgemein-, Tropen- und Reisemedizin, München.
Jörg SchellingHausärztliche Gemeinschaftspraxis Martinsried, München.
Klaus WahleMedizinische Fakultät - Universität Münster.
Dietmar BeierSächsische Impfkommission, Chemnitz.
Anja KwetkatKlinik für Geriatrie und Palliativmedizin - Klinikum Osnabrück.
Tino F SchwarzInstitut für Labormedizin und Impfzentrum, Klinikum Würzburg Mitte gGmbH, Standort Juliusspital, Würzburg.
Klinikum Osnabrück · DEKlinikum Würzburg Mitte · DEPraxis · EEPraxis für Humangenetik · DEUniversity of Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Seasonal influenza causes a significant burden of disease in the German population and is associated with high societal costs. Persons aged 60 years and older are particularly at risk due to immunosenescence and chronic disease and account for a large proportion of influenza-associated hospitalizations and deaths. Adjuvanted, high-dose, recombinant and cell-based influenza vaccines have been developed to improve the effectiveness compared with conventional vaccines. Recent observational studies show better effectiveness of adjuvanted vaccine over conventional vaccines and similar effectiveness to the high-dose vaccine in older adults. Some countries have already considered the new evidence in their vaccination recommendations for the current or earlier seasons. The availability of the vaccines for older adults should also be ensured in Germany to guarantee a high level of vaccination protection.

Indexed as

ImmunosenescenceInfluenza, HumanInfluenza VaccinesAgedHumansMiddle AgedSeasonsVaccinationInfluenza Vaccines

Identifiers

PMID36990440
PMCPMC10413204
OpenAlexW4361297419

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.