Evidence map›Paper›PMID 36990378›Full record

ArticleBiological psychology2023

HPA-SAM co-activation among racially diverse, economically disadvantaged early adolescents: Secondary analysis with a preliminary test of a multisystem, person-centered approach.

Holly T Pham, Jason José Bendezú, Martha E Wadsworth

Abstract read
In one paragraph

Article in Biological psychology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Stress System Concordance: A Signature of Resilience.Biological psychiatry global open science · 2025
    Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Holly T PhamDepartment of Psychology, 234 Moore Building, The Pennsylvania State University, University Park, PA 16802, United States. Electronic address: hxp252@psu.edu.
Jason José BendezúDepartment of Psychology, 234 Moore Building, The Pennsylvania State University, University Park, PA 16802, United States.
Martha E WadsworthDepartment of Psychology, 234 Moore Building, The Pennsylvania State University, University Park, PA 16802, United States.

Funding

PREVENTION AND METHODOLOGY TRAINING (PAMT)T32DA017629 · NIDA · PENNSYLVANIA STATE UNIVERSITY-UNIV PARK · PI Eric D Claus, Rina D Eiden · 2005 to 2026
$9.5M
Preventing Internalizing Psychopathology in Preadolescents Exposed to Chronic StressR33MH107631 · NIMH · PENNSYLVANIA STATE UNIVERSITY, THE · PI WADSWORTH, MARTHA E · 2018 to 2021
$2.5M
Preventing Internalizing Psychopathology in Preadolescents Exposed to Chronic StressR21MH107631 · NIMH · PENNSYLVANIA STATE UNIVERSITY, THE · PI WADSWORTH, MARTHA E · 2016 to 2017
$1.1M
NIDA NIH HHS T32 DA017629NIMH NIH HHS R21 MH107631NIMH NIH HHS R33 MH107631
6 · The paper itself

Abstract

Investigating the co-activation of hypothalamic-pituitary-adrenal (HPA) and sympathetic-adrenomedullary (SAM) responses to acute stress can provide insight into how risk might become biologically embedded during early adolescence and improve understanding of what distinguishes physiological dysregulation from normative/expected physiological responses to stress. Evidence has thus far been mixed as to whether symmetric or asymmetric co-activation patterns are associated with higher exposure to chronic stress and poorer mental health outcomes during adolescence. This study expands on a prior multisystem, person-centered analysis of lower-risk, racially homogenous youth by focusing on HPA-SAM co-activation patterns in a higher-risk, racially diverse sample of early adolescents from low-income families (N = 119, M

Indexed as

Hypothalamo-Hypophyseal SystemStress, PsychologicalAdolescentalpha-AmylasesEmotionsFemaleHumansHydrocortisoneMalePituitary-Adrenal SystemSalivaalpha-AmylasesHydrocortisoneAdolescenceAlpha-amylaseCortisolMultisystemMultitrajectory modeling

Identifiers

PMID36990378
PMCPMC10175235

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.