Evidence map›Paper›PMID 36990274›Full record

ArticleContemporary clinical trials2023

Acupuncture for chronic low back pain in older adults: Design and protocol for the BackInAction pragmatic clinical trial.

Lynn L DeBar, Morgan Justice, Andrew L Avins, Andrea Cook, Carolyn M Eng, Patricia M Herman, Clarissa Hsu, Arya Nielsen, Alice Pressman, Katie L Stone and 2 more

2 registry-linked trialsOpen access · hybridAbstract readClinical Trial Protocol
In one paragraph

Article in Contemporary clinical trials, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04982315 nacompletednot on this map

Pragmatic Trial of Acupuncture for Chronic Low Back Pain in Older Adults

TypeinterventionalSponsorKaiser PermanenteRan2021 to 2024Enrolled807ConditionsChronic Low-back PainArmsStandard Acupuncture, Enhanced Acupuncture
NCT07296653 early_phase1recruitingnot on this mapstarted 2025, after this paper: background citation

Efficacy of Prolotherapy in Acupoints in Chronic Non-specific Low Back Pain (cLBP) - A Randomized Control Trial

TypeinterventionalSponsorNational and Kapodistrian University of AthensRan2025 to 2027Enrolled60ConditionsChronic Non-specific Low Back PainArmsDextrose 15% and lidocaine 1% infiltration, Lidocaine 1% infiltration
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 1 country.

Lynn L DeBarKaiser Permanente Washington Health Research Institute, Seattle, WA, United States of America. Electronic address: lynn.debar@kp.org.
Morgan JusticeKaiser Permanente Washington Health Research Institute, Seattle, WA, United States of America.
Andrew L AvinsKaiser Permanente Northern California Division of Research, Oakland, CA, United States of America; University of California Department of Epidemiology and Biostatistics, San Francisco, CA, United States of America.
Andrea CookKaiser Permanente Washington Health Research Institute, Seattle, WA, United States of America.
Carolyn M EngKaiser Permanente Washington Health Research Institute, Seattle, WA, United States of America.
Patricia M HermanRAND, Santa Monica, CA, United States of America.
Clarissa HsuKaiser Permanente Washington Health Research Institute, Seattle, WA, United States of America.
Arya NielsenIcahn School of Medicine at Mount Sinai, Department of Family Medicine & Community Health, New York, NY, United States of America.
Alice PressmanUniversity of California Department of Epidemiology and Biostatistics, San Francisco, CA, United States of America; Sutter Health California Pacific Medical Center Research Institute, San Francisco, CA, United States of America; Sutter Health Center for Health Systems Research, Walnut Creek, CA, United States of America.
Katie L StoneUniversity of California Department of Epidemiology and Biostatistics, San Francisco, CA, United States of America; Sutter Health California Pacific Medical Center Research Institute, San Francisco, CA, United States of America.
Raymond Y TeetsInstitute for Family Health, New York, NY, United States of America.
Robert WellmanKaiser Permanente Washington Health Research Institute, Seattle, WA, United States of America.
Kaiser Permanente Washington Health Research Institute · USSutter Health · USIcahn School of Medicine at Mount Sinai · USInstitute for Family Health · USKaiser Permanente · USRAND Corporation · US

Funding

NIH Health Care Systems Research Collaboratory-Coordinating Center (U24)U24AT009676 · NCCIH · DUKE UNIVERSITY · PI LESLEY H CURTIS, Adrian Hernandez · 2017 to 2026
$21.5M
Pragmatic Trial of Acupuncture for Chronic Low Back Pain in Older AdultsUH3AT010739 · NCCIH · KAISER FOUNDATION RESEARCH INSTITUTE · PI COOK, ANDREA JEAN, DEBAR, LYNN L. · 2020 to 2022
$9.1M
HEAL Collaboratory Resource Coordinating Center (PRISM) (U24): Bioethics SupplementU24AT010961 · NCCIH · DUKE UNIVERSITY · PI CURTIS, LESLEY H, HERNANDEZ, ADRIAN · 2019 to 2021
$6.4M
Pragmatic Trial of Acupuncture for Chronic Low Back Pain in Older AdultsUG3AT010739 · NCCIH · KAISER FOUNDATION RESEARCH INSTITUTE · PI DEBAR, LYNN L., SHERMAN, KAREN J · 2019 to 2019
$1.2M
NCCIH NIH HHS U24 AT009676NCCIH NIH HHS U24 AT010961NCCIH NIH HHS UG3 AT010739NCCIH NIH HHS UH3 AT010739
6 · The paper itself

Abstract

backgroundBack pain prevalence and burden increase with age; approximately one-third of U.S. adults 65 years of age and older experience lower back pain (LBP). For chronic low back pain (cLBP), typically defined as lasting three months or longer, many treatments for younger adults may be inappropriate for older adults given their greater prevalence of comorbidities with attendant polypharmacy. While acupuncture has been demonstrated to be safe and effective for cLBP in adults overall, few studies of acupuncture have either included or focused on adults ≥65 years old.

methodsThe BackInAction study is a pragmatic, multi-site, three-arm, parallel-groups randomized controlled trial designed to test the effectiveness of acupuncture needling for improving back pain-related disability among 807 older adults ≥65 years old with cLBP. Participants are randomized to standard acupuncture (SA; up to 15 treatment sessions across 12 weeks), enhanced acupuncture (EA; SA during first 12 weeks and up to 6 additional sessions across the following 12 weeks), and usual medical care (UMC) alone. Participants are followed for 12 months with study outcomes assessed monthly with the primary outcome timepoint at 6 months. DISCUSSION: The BackInAction study offers an opportunity to further understand the effectiveness, dose-dependence, and safety of acupuncture in a Medicare population. Additionally, study results may encourage broader adoption of more effective, safer, and more satisfactory options to the continuing over-reliance on opioid- and invasive medical treatments for cLBP among older adults.

trial registrationClinicalTrials.gov Identifier: NCT04982315. Clinical trial registration date: July 29, 2021.

Indexed as

Acupuncture TherapyChronic PainLow Back PainAgedBack PainHumansMulticenter Studies as TopicPragmatic Clinical Trials as TopicRandomized Controlled Trials as TopicTreatment OutcomeAcupunctureChronic low back painOlder adultsPragmatic clinical trial

Identifiers

PMID36990274
PMCPMC10416311
OpenAlexW4360999331

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.