Evidence map›Paper›PMID 36990264›Full record

ReviewFertility and sterility2023

Pros and cons of Mendelian randomization.

Heping Zhang

Abstract readReview
In one paragraph

Review in Fertility and sterility, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  6. CD4Combinatorial chemistry & high throughput screening · 2026
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  7. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Heping ZhangDepartment of Biostatistics, Yale University School of Public Health, New Haven, Connecticut. Electronic address: heping.zhang@yale.edu.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Pre-IVF treatment with a GnRH antagonist in women with endometriosis - A prospective double blind placebo controlled trial (Pregnant) - Application 1/4R01HD100336 · NICHD · YALE UNIVERSITY · PI TAYLOR, HUGH SMITH, ZHANG, HEPING · 2019 to 2023
$5.5M
Analysis of Big Data Squared in Biomedical StudiesR01MH116527 · NIMH · YALE UNIVERSITY · PI ZHANG, HEPING · 2018 to 2022
$2.3M
Reproductive Medicine Collaborative Consortium: a randomized placebo-controlled trial of EGCG to improve fertility in women with uterine fibroids- Application 4/4R01HD100369 · NICHD · YALE UNIVERSITY · PI TAYLOR, HUGH SMITH, ZHANG, HEPING · 2019 to 2023
$1.7M
Analysis of Genomic and Complex DataR01HG010171 · NHGRI · YALE UNIVERSITY · PI ZHANG, HEPING · 2019 to 2022
$1.4M
NCATS NIH HHS UL1 TR001863NHGRI NIH HHS R01 HG010171NICHD NIH HHS R01 HD100336NICHD NIH HHS R01 HD100369NIMH NIH HHS R01 MH116527
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Mendelian Randomization AnalysisSmoking CessationHumansSmoking

Identifiers

PMID36990264
PMCPMC10234673

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.