Evidence map›Paper›PMID 36989875›Full record

ArticleBiophysical chemistry2023

In-cell

June M Kenyaga, Sarah A Oteino, Yan Sun, Wei Qiang

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biophysical chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

June M KenyagaDepartment of Chemistry, Binghamton University, Vestal, NY 13850, USA.
Sarah A OteinoDepartment of Chemistry, Binghamton University, Vestal, NY 13850, USA.
Yan SunSmall Scale Systems Integration and Packaging (S3IP), Binghamton University, Vestal, NY 13850, USA.
Wei QiangDepartment of Chemistry, Binghamton University, Vestal, NY 13850, USA. Electronic address: wqiang@binghamton.edu.
Binghamton University · US

Funding

Molecular Structural Basis of Non-specific Neuronal Membrane Disruption Induced by Early-Stage Beta-Amyloid Peptide AggregationR01GM125853 · NIGMS · STATE UNIVERSITY OF NY,BINGHAMTON · PI Wei Qiang · 2018 to 2026
$2.5M
NIGMS NIH HHS R01 GM125853
6 · The paper itself

Abstract

Non-specific disruption of cellular membranes induced by aggregation of exogeneous β-amyloid (Aβ) peptides is considered a viable pathological mechanism in Alzheimer's disease (AD). The solid-state nuclear magnetic resonance (ssNMR) spectroscopy has been widely applied in model liposomes to provide important insights on the molecular interactions between membranes and Aβ aggregates. Yet, the feasibility of in-cell ssNMR spectroscopy to probe Aβ-membrane interactions in native cellular environments has rarely been tested. Here we report the application of in-cell

Indexed as

Alzheimer DiseaseNeuroblastomaAmyloid beta-PeptidesAnimalsLiposomesMagnetic Resonance SpectroscopyMiceNuclear Magnetic Resonance, BiomolecularPhospholipidsAmyloid beta-PeptidesLiposomesPhospholipids(31)P solid-state NMRIn-cell NMR spectroscopyMembrane disruptionNeuroblastoma neuro-2a cellsβ-Amyloid peptides

Identifiers

PMID36989875
PMCPMC11837396
OpenAlexW4328103190

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.