Evidence map›Paper›PMID 36989747›Full record

ArticleComputers in biology and medicine2023

Automatic segmentation of abdominal aortic aneurysms from CT angiography using a context-aware cascaded U-Net.

Nan Mu, Zonghan Lyu, Mostafa Rezaeitaleshmahalleh, Xiaoming Zhang, Todd Rasmussen, Robert McBane, Jingfeng Jiang

Abstract read
In one paragraph

Article in Computers in biology and medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nan MuBiomedical Engineering, Michigan Technological University, Houghton, MI, 49931, USA.
Zonghan LyuBiomedical Engineering, Michigan Technological University, Houghton, MI, 49931, USA.
Mostafa RezaeitaleshmahallehBiomedical Engineering, Michigan Technological University, Houghton, MI, 49931, USA.
Xiaoming ZhangMayo Clinic, Rochester, MN, 55902, USA.
Todd RasmussenMayo Clinic, Rochester, MN, 55902, USA.
Robert McBaneMayo Clinic, Rochester, MN, 55902, USA.
Jingfeng JiangBiomedical Engineering, Michigan Technological University, Houghton, MI, 49931, USA; Center for Biocomputing and Digital Health, Health Research Institute, Institute of Computing and Cybernetics, Michigan Technological University, Houghton, MI, 49931, USA. Electronic address: jjiang1@mtu.edu.

Funding

Personalized Management of Intracranial Aneurysms Using Computer-aided AnalyticsR01EB029570 · NIBIB · MICHIGAN TECHNOLOGICAL UNIVERSITY · PI JIANG, JINGFENG · 2021 to 2024
$1.3M
American Heart Association-American Stroke Association 23POST1022454NIBIB NIH HHS R01 EB029570
6 · The paper itself

Abstract

We delineate abdominal aortic aneurysms, including lumen and intraluminal thrombosis (ILT), from contrast-enhanced computed tomography angiography (CTA) data in 70 patients with complete automation. A novel context-aware cascaded U-Net configuration enables automated image segmentation. Notably, auto-context structure, in conjunction with dilated convolutions, anisotropic context module, hierarchical supervision, and a multi-class loss function, are proposed to improve the delineation of ILT in an unbalanced, low-contrast multi-class labeling problem. A quantitative analysis shows that the automated image segmentation produces comparable results with trained human users (e.g., DICE scores of 0.945 and 0.804 for lumen and ILT, respectively). Resultant morphological metrics (e.g., volume, surface area, etc.) are highly correlated to those parameters generated by trained human users. In conclusion, the proposed automated multi-class image segmentation tool has the potential to be further developed as a translational software tool that can be used to improve the clinical management of AAAs.

Indexed as

Aortic Aneurysm, AbdominalComputed Tomography AngiographyAngiographyHumansImage Processing, Computer-AssistedTomography, X-Ray ComputedAbdominal aortic aneurysmContext-awareDeep-learningGeometrical analysisImage segmentationNeural network

Identifiers

PMID36989747
PMCPMC10625464

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.