Evidence map›Paper›PMID 36989654›Full record

ArticleCytokine2023

T-cell lymphocytopenia: An omnipresent predictor of morbidity and mortality in consequence of SARS-CoV disease and influenza A infections.

Jeffrey S Putter, Jerard Seghatchian

Abstract read
In one paragraph

Article in Cytokine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jeffrey S PutterMedical Biomechanics Inc., 100 E. San Marcos Blvd. #400, North San Diego County, CA 92069, USA. Electronic address: Jputter@LTSP.com.
Jerard SeghatchianInternational Consultancy in Modern Precision Personalized Blood Component Therapies, London, England, UK. Electronic address: jseghatchian@btopenworld.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of the researchWe proposed T-cell lymphocytopenia as a strategic predictor of serious coronavirus and influenza infections. Our preeminent goal was to determine whether a degree of T-cell lymphopenia would identify a distinct threshold cell count to differentiate between severe and non-severe infections. We codified an Index Severity Score to exploit an association between T-cell cytopenia and the grade of disease activity. PRINCIPAL

resultA T-cell count of 560 cells/uL or below signified a trend towards advanced disease. KEY FINDINGS AND

conclusions

Indexed as

Influenza, HumanLymphopeniaSevere acute respiratory syndrome-related coronavirusHumansMorbidityT-LymphocytesIndex Severity Score of infectionInfluenza virusSARS-CoV diseaseT-cell apoptosis and sequestrationT-cell differential countsT-cell lymphocytopenia

Identifiers

PMID36989654
PMCPMC9933323

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.