Evidence map›Paper›PMID 36989211›Full record

ArticlePLOS global public health2023

Back to the basics: Clinical assessment yields robust mortality prediction and increased feasibility in low resource settings.

Mark T Yost, Melissa M Carvalho, Lidwine Mbuh, Fanny N Dissak-Delon, Rasheedat Oke, Debora Guidam, Rene M Nlong, Mbengawoh M Zikirou, David Mekolo, Louis H Banaken and 3 more

Abstract read
In one paragraph

Article in PLOS global public health, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Mark T YostDepartment of Surgery, Program for the Advancement of Surgical Equity, University of California Los Angeles, Los Angeles, California, United States of America.ORCID https://orcid.org/0000-0001-6277-7729
Melissa M CarvalhoDepartment of Surgery, Program for the Advancement of Surgical Equity, University of California Los Angeles, Los Angeles, California, United States of America.ORCID https://orcid.org/0000-0002-9607-0999
Lidwine MbuhFaculty of Health Sciences, University of Buea, Buea, Cameroon.
Fanny N Dissak-DelonLittoral Regional Delegation, Ministry of Public Health, Yaoundé, Cameroon.ORCID https://orcid.org/0000-0001-8386-6501
Rasheedat OkeDepartment of Surgery, Program for the Advancement of Surgical Equity, University of California Los Angeles, Los Angeles, California, United States of America.
Debora GuidamFaculty of Health Sciences, University of Buea, Buea, Cameroon.
Rene M NlongFaculty of Health Sciences, University of Buea, Buea, Cameroon.
Mbengawoh M ZikirouFaculty of Health Sciences, University of Buea, Buea, Cameroon.
David MekoloFaculty of Health Sciences, University of Buea, Buea, Cameroon.
Louis H BanakenFaculty of Health Sciences, University of Buea, Buea, Cameroon.
Catherine JuillardDepartment of Surgery, Program for the Advancement of Surgical Equity, University of California Los Angeles, Los Angeles, California, United States of America.ORCID https://orcid.org/0000-0003-0847-8933
Alain Chichom-MefireFaculty of Health Sciences, University of Buea, Buea, Cameroon.ORCID https://orcid.org/0000-0001-7230-567X
S Ariane ChristieDepartment of Surgery, Program for the Advancement of Surgical Equity, University of California Los Angeles, Los Angeles, California, United States of America.

Funding

Building Capacity for Trauma Quality Improvement: An Innovative Pilot Program in Cameroon to Address the Burden of InjuryR21TW010453 · FIC · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CHICHOM, ALAIN MEFIRE, JUILLARD, CATHERINE · 2018 to 2019
$318k
FIC NIH HHS R21 TW010453
6 · The paper itself

Abstract

introductionMortality prediction aids clinical decision-making and is necessary for trauma quality improvement initiatives. Conventional injury severity scores are often not feasible in low-resource settings. We hypothesize that clinician assessment will be more feasible and have comparable discrimination of mortality compared to conventional scores in low and middle-income countries (LMICs).

methodsBetween 2017 and 2019, injury data were collected from all injured patients as part of a prospective, four-hospital trauma registry in Cameroon. Clinicians used physical exam at presentation to assign a highest estimated abbreviated injury scale (HEAIS) for each patient. Discrimination of hospital mortality was evaluated using receiver operating characteristic curves. Discrimination of HEAIS was compared with conventional scores. Data missingness for each score was reported.

resultsOf 9,635 presenting with injuries, there were 206 in-hospital deaths (2.2%). Compared to 97.5% of patients with HEAIS scores, only 33.2% had sufficient data to calculate a Revised Trauma Score (RTS) and 24.8% had data to calculate a Kampala Trauma Score (KTS). Data from 2,328 patients with all scores was used to compare models. Although statistically inferior to the prediction generated by RTS (AUC 0.92-0.98) and KTS (AUC 0.93-0.99), HEAIS provided excellent overall discrimination of mortality (AUC 0.84-0.92). Among 9,269 patients with HEAIS scores was strongly predictive of mortality (AUC 0.93-0.96).

conclusionClinical assessment of injury severity using HEAIS strongly predicts hospital mortality and far exceeds conventional scores in feasibility. In contexts where traditional scoring systems are not feasible, utilization of HEAIS could facilitate improved data quality and expand access to quality improvement programming.

Identifiers

PMID36989211
PMCPMC10057736

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.