Evidence map›Paper›PMID 36988878›Full record

ArticleAdvances in experimental medicine and biology2023

Mechanism of the Regulation of Plasma Cholesterol Levels by PI(4,5)P

Yuanyuan Qin, Marisa W Medina

Abstract read
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In one paragraph

Article in Advances in experimental medicine and biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 91% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yuanyuan QinDepartment of Pediatrics, Division of Cardiology, University of California, San Francisco, Oakland, CA, USA.
Marisa W MedinaDepartment of Pediatrics, Division of Cardiology, University of California, San Francisco, Oakland, CA, USA. marisa.medina@ucsf.edu.
University of California, San Francisco · US

Funding

The Role of Phosphatidylinositides in Lipid MetabolismR01HL139902 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI MEDINA, MARISA WONG · 2018 to 2021
$1.7M
NHLBI NIH HHS R01 HL139902
6 · The paper itself

Abstract

Elevated low-density lipoprotein (LDL) cholesterol (LDLc) is one of the most well-established risk factors for cardiovascular disease, while high levels of high-density lipoprotein (HDL) cholesterol (HDLc) have been associated with protection from cardiovascular disease. Cardiovascular disease remains one of the leading causes of death worldwide; thus it is important to understand mechanisms that impact LDLc and HDLc metabolism. In this chapter, we will discuss molecular processes by which phosphatidylinositol-(4,5)-bisphosphate, PI(4,5)P

Indexed as

Cardiovascular DiseasesCholesterolCholesterol, HDLCholesterol, LDLHumansLipoproteinsCholesterolCholesterol, HDLCholesterol, LDLLipoproteinsApoA1ApoBLDLcLDLRLysosomeTMEM55B

Identifiers

PMID36988878
OpenAlexW4361304566

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.