Evidence map›Paper›PMID 36988677›Full record

ArticleGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2023

Topographic patterns of retinal lesions in multiple evanescent white dot syndrome.

Ariel Yuhan Ong, Johannes Birtel, Eleftherios Agorogiannis, Srilakshmi M Sharma, Peter Charbel Issa

Open access · hybridAbstract read
In one paragraph

Article in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Clinical characteristics of multiple evanescent white dot syndrome with poor visual prognosis in Japanese patients.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
  2. Review
  3. Article
  4. Observational
  5. Centrifugal progression of retinal lesions in the early evolution of multiple evanescent white dot syndrome.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
  6. Review
  7. Reply to: In response to: Topographic patterns of retinal lesions in multiple evanescent white dot syndrome.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Ariel Yuhan OngOxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Johannes BirtelOxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Eleftherios AgorogiannisOxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Srilakshmi M SharmaOxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK.
Peter Charbel IssaOxford Eye Hospital, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. study-enquiry@outlook.com.ORCID http://orcid.org/0000-0002-0351-6673
Nuffield Orthopaedic Centre · GBOxford University Hospitals NHS Trust · GBUniversität Hamburg · DE

Funding

Dr. Werner Jackstädt-Stiftung S0134-10.22
6 · The paper itself

Abstract

purposeTo demonstrate different topographic distributions of multiple-evanescent white dot syndrome (MEWDS) and secondary MEWDS disease and to describe possible associations.

methodsClinical evaluation and multimodal retinal imaging in 27 subjects with MEWDS (29 discrete episodes of MEWDS). Ophthalmic assessment included best-corrected visual acuity testing and multimodal retinal imaging with OCT, blue-light autofluorescence, fluorescein and indocyanine green angiography, fundus photography, and widefield pseudocolor and autofluorescence fundus imaging.

resultsThe topographic distribution of MEWDS lesions was centered on or around the optic disc (n = 17, 59%), centered on the macula (n = 7, 24%), sectoral (n = 2, 7%), or was indeterminate (n = 3, 10%). The MEWDS episodes either occurred in the absence ('primary MEWDS'; n = 14, 48%) or presence of concurrent chorioretinal pathology ('secondary MEWDS'; n = 15, 52%). In patients with the latter, MEWDS lesions were often centered around a coexisting chorioretinal lesion. The majority of patients in both groups experienced resolution of their symptoms and retinal changes on multimodal imaging by 3 months.

conclusionsDistinct distributions of MEWDS lesions were identified. MEWDS may occur in tandem with other chorioretinal pathology, which may impact the topography of MEWDS lesions.

Indexed as

Retinal DiseasesWhite Dot SyndromesFluorescein AngiographyHumansRetinaTomography, Optical CoherenceAngiographyFundus autofluorescenceMultimodal imagingMultiple evanescent white dot syndromeMyopiaOptical coherence tomography

Identifiers

PMID36988677
PMCPMC10368570
OpenAlexW4361300691

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.