ArticleAging2023
Association between the sarcopenia index and the risk of stroke in elderly patients with hypertension: a cohort study.
Article in Aging, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 28 citations in OpenAlex.
- Cost-effectiveness of opportunistic CT versus clinical methods for sarcopenia screening.Skeletal radiology · 2026Article
- Malnutrition and Cachexia in Inpatients With Acute Cardiac Conditions: A Scientific Statement From the American Heart Association.Circulation · 2026Review
- Associations between sarcopenic obesity and the risk of cardiovascular-kidney-metabolic syndrome progression: insights from the China health and retirement longitudinal study.Diabetology & metabolic syndrome · 2025Article
- Evaluating the role of CHG index in predicting stroke risk among adults with varying glucose regulation.Aging clinical and experimental research · 2025Article
- Interaction effects of dietary carotenoid intake and gamma-glutamyl transferase level on the prevalence of stroke in older adults.Journal of health, population, and nutrition · 2025Observational
- Mediating role of possible sarcopenia in the association between diabetes and stroke: finding from the China health and retirement longitudinal study.BMC geriatrics · 2025Article
- Triglyceride-glucose index combined with estimated pulse wave velocity improves stroke risk stratification in the CHARLS cohort.Scientific reports · 2025Article
- Article
- Dynapenic abdominal obesity and the risks of heart disease and all-cause mortality: a 7-year longitudinal study among middle-aged and older Chinese adults.BMC public health · 2025Article
- Article
- The value of triglyceride-glucose index-related indices in evaluating migraine: perspectives from multi-centre cross-sectional studies and machine learning models.Lipids in health and disease · 2025Article
- Association Between the Serum Creatinine to Cystatin C Ratio and Cardiovascular Disease in Middle-Aged and Older Adults in China: A Nationwide Cohort Study.Journal of the American Heart Association · 2025Article
- Predictive values of four nutritional indices for adverse outcomes in patients with hypertension.Clinical and experimental nephrology · 2025Article
- Association between the hemoglobin A1c/High-density lipoprotein cholesterol ratio and stroke incidence: a prospective nationwide cohort study in China.Lipids in health and disease · 2025Article
- The association of HALP score with low muscle mass in older adults.Frontiers in nutrition · 2025Article
- Longitudinal relationship between baseline Weight-Adjusted Waist Index and stroke risk over 8 years in Chinese adults aged 45 and older: a prospective cohort study.Frontiers in public health · 2025Article
- Association of visceral adiposity index and lipid accumulation product with frailty in U.S. adults: a cross-sectional study from NHANES.Lipids in health and disease · 2024Article
- The ZJU index is associated with the risk of sarcopenia in American adults aged 20-59: a cross-sectional study.Lipids in health and disease · 2024Article
- Association between weight-adjusted waist index with incident stroke in the elderly with hypertension: a cohort study.Scientific reports · 2024Article
- Insulin resistance and sarcopenia: a prognostic longitudinal link to stroke risk in middle-aged and elderly Chinese population.BMC public health · 2024Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The purpose of this study was to investigate the relationship between the sarcopenia index (SI) and stroke risk in elderly patients with hypertension. This study included 5145 stroke-free elderly hypertensive patients. We used Cox regression models to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) of incident stroke. Over a median follow-up of 38 months, we identified 607 (11.80%) individuals with total stroke, of whom 507 (9.85%) had ischemic stroke and 93 (1.81%) had hemorrhagic stroke. The risk of developing stroke decreased with each quartile of SI; after adjustment for multiple confounders, the HRs for the Q4 group versus the Q1 group were 0.46 (95% CI, 0.35-0.59) for total stroke, 0.46 (95% CI, 0.35-0.61) for ischemic stroke, and 0.33 (95% CI, 0.17-0.64) for hemorrhagic stroke. Restricted cubic spline analysis also demonstrated a cumulative increase in the risk of total stroke with decreases in the SI. The addition of SI to the conventional model for total stroke improved (ΔC-statistics = 0.02), an integrated discrimination improvement of 0.03 (95% CI, 0.02-0.04), and a net reclassification improvement of 0.17 (95% CI, 0.10-0.23). Similar results were observed for ischemic stroke and hemorrhagic stroke. This study found that elevated SI was negatively associated with the risk of stroke in elderly patients with hypertension. Uncovering the causality behind the relationship requires further prospective study.
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