Evidence map›Paper›PMID 36987691›Full record

ArticleJournal of diabetes investigation2023

Association of stressful life events with cognitive impairment in patients with type 2 diabetes mellitus.

Lina Wang, Shanshan Dong, Chenxu Zhao, Zhaoyu Gao, Lei Jiang, Rui Zhang, Tingting Shen, Yingying Guo, Huimin Zhou, Shunjiang Xu

Open access · goldAbstract read
In one paragraph

Article in Journal of diabetes investigation, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 1 country.

Lina Wang *Department of Endocrinology and Metabolism, The First Hospital of Hebei Medical University, Shijiazhuang, China.ORCID https://orcid.org/0000-0003-1033-7072
Shanshan Dong *Department of Endocrinology and Metabolism, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Chenxu ZhaoDepartment of Endocrinology and Metabolism, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Zhaoyu GaoCentral Laboratory, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Lei JiangCentral Laboratory, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Rui ZhangCentral Laboratory, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Tingting ShenDepartment of Endocrinology and Metabolism, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Yingying GuoDepartment of Endocrinology and Metabolism, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Huimin ZhouDepartment of Endocrinology and Metabolism, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Shunjiang XuCentral Laboratory, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Hebei Medical University · CN

Funding

Special Funding for Local Science and Technology Development Guided by the Central Government 206Z7701Gthe Key Projects of Hebei Administration of Traditional Chinese Medicine Z2022015The Science and Technology project of the People's Livelihood in Hebei Province 20377707D
6 · The paper itself

Abstract

AIMS/

introductionThis study was carried out to investigate the relationship of stressful life events (SLEs) with the risk of cognitive impairment in patients with type 2 diabetes mellitus. MATERIALS AND

methodsA total of 316 patients with type 2 diabetes mellitus aged >45 years were recruited in this study, and data on demographics, medical history, lifestyle characteristics and SLEs were collected. The cognitive status of patients was evaluated with a battery of cognitive function scales. Logistic regression analyses were carried out to evaluate the risk and protective factors for mild cognitive impairment (MCI).

resultsParticipants, including 217 type 2 diabetes mellitus patients with MCI and 99 patients without MCI, were enrolled in the current study. Among the SLEs, the death of an offspring or parent (odds ratio [OR] 1.994, 95% confidence interval [CI] 1.017-3.908) was a risk factor for MCI after adjustment for age and education level. In the subgroup of participants aged <60 years, the death of an offspring or parent (OR 2.731, 95% CI 1.119-6.665) and financial difficulty (OR 22.205, 95% CI 4.365-112.966) were risk factors for the development of MCI, whereas high working pressure (OR 0.154, 95% CI 0.048-0.495) and career changes (OR 0.324, 95% CI 0.124-0.847) were protective factors for MCI.

conclusionsThese data suggested that SLEs were associated with cognitive function in patients with type 2 diabetes mellitus. Adverse life events, such as the death of an offspring or parent, were risk factors for cognitive impairment, whereas high work pressure in middle-aged people was a protective factor against cognitive impairment.

Indexed as

Cognitive DysfunctionDiabetes Mellitus, Type 2HumansLife StyleMiddle AgedRisk FactorsMild cognitive impairmentStressful life eventsType 2 diabetes mellitus

Identifiers

PMID36987691
PMCPMC10204176
OpenAlexW4361288593

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.