Evidence map›Paper›PMID 36987690›Full record

SynthesisInterventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences2026

Under (back) pressure: Better collateral flow may facilitate clot removal in ischemic stroke: A systematic review and meta-analysis.

Trey Seymour, Hassan Kobeissi, Sherief Ghozy, Rishabh Gupta, Ramanathan Kadirvel, David F Kallmes

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Interventional neuroradiology : journal of peritherapeutic neuroradiology, surgical procedures and related neurosciences, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Trey SeymourUniversity of Denver College of Natural Science and Mathematics, CO, USA.ORCID 0000-0002-1824-077X
Hassan KobeissiCentral Michigan University of Medicine, Mt. Pleasant, MI, USA.ORCID 0000-0001-7446-624X
Sherief GhozyDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0001-5629-3023
Rishabh GuptaDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.
Ramanathan KadirvelDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-6786-9953
David F KallmesDepartment of Radiology, Mayo Clinic, Rochester, MN, USA.ORCID 0000-0002-8495-0040

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BackgroundCollateral status may facilitate clot removal and affect rates of successful reperfusion following endovascular therapy (EVT) for acute ischemic stroke (AIS).MethodsFollowing the PRISMA guidelines, a systematic literature review of the English language literature was conducted using PubMed, Scopus, Web of Science, and Embase. Papers which focused on collateral status and patients treated with EVT for AIS were included in our analysis. Outcomes of interest included collateral score grading, rates of successful reperfusion defined as thrombolysis in cerebral infarction (TICI) score 2b-3 and onset to revascularization time. We calculated pooled odds ratio (OR) or mean difference (MD) and their corresponding 95% confidence intervals (CI) based on collateral status.Results16 studies, with 6073 patients, were included in our analysis. Among the included studies, there were six different collateral grading scales, which were dichotomized into "good to moderate" and "poor" collaterals. Odds of successful reperfusion were significantly higher among patients with good to moderate collateral circulation compared to those with poor collaterals (OR =  1.61; 95% CI = 1.24 to 2.09;

Indexed as

Collateral CirculationEndovascular ProceduresIschemic StrokeThrombectomyHumansTreatment OutcomeCollateral flowCollateral statusreperfusionthrombectomyTICI

Identifiers

PMID36987690
PMCPMC13305646

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.