Evidence map›Paper›PMID 36987501›Full record

ArticleNature reviews bioengineering2023

Biomaterials for intranasal and inhaled vaccine delivery.

Devorah Cahn, Mayowa Amosu, Katharina Maisel, Gregg A Duncan

Open access · bronzeAbstract read
In one paragraph

Article in Nature reviews bioengineering, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 33 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
  8. A comprehensive comparison of DNA and RNA vaccines.Advanced drug delivery reviews · 2024
    Review
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Perspectives on Multiscale Colloid-Based Materials for Biomedical Applications.Langmuir : the ACS journal of surfaces and colloids · 2023
    Review
  16. Aerosol pulmonary immune engineering.Advanced drug delivery reviews · 2023
    Review
  17. Review
  18. Chemical science · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Devorah CahnFischell Department of Bioengineering, University of Maryland, College Park, MD, USA.
Mayowa AmosuFischell Department of Bioengineering, University of Maryland, College Park, MD, USA.
Katharina MaiselFischell Department of Bioengineering, University of Maryland, College Park, MD, USA.
Gregg A DuncanFischell Department of Bioengineering, University of Maryland, College Park, MD, USA.ORCID 0000-0002-6811-1327
Horse Hospital · GBUniversity of Maryland, College Park · US

Funding

Understanding alterations to mucus composition and function in asthmaR01HL160540 · NHLBI · UNIV OF MARYLAND, COLLEGE PARK · PI Gregg Duncan · 2022 to 2026
$2.1M
NHLBI NIH HHS R01 HL160540
6 · The paper itself

Abstract

Delivery of vaccines by nasal sprays may enable more robust, protective mucosal immune responses against infectious diseases, such as COVID-19, compared with intramuscular injection. In this Comment, we highlight how biomaterials can be designed to allow intranasal and inhaled vaccination.

Identifiers

PMID36987501
PMCPMC10041562
OpenAlexW4317830723

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.