ArticlePolymers2023
Medical-Grade Poly(Lactic Acid)/Hydroxyapatite Composite Films: Thermal and In Vitro Degradation Properties.
Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed.
- Design and Characterization of 3D Printed Auxetic PLA-HA Composite Scaffolds for Biomedical Application.Materials (Basel, Switzerland) · 2026Article
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- Highly Efficient Biodegradation of Postconsumer Polylactic Acid Waste: The First Report onInternational journal of microbiology · 2026Article
- Material Extrusion of the Poly(lactic acid)/HAp Nanocomposite Scaffold for Bone Tissue Applications: A Comprehensive Investigation.ACS omega · 2025Article
- Green Synthesis of Multi-Walled Carbon Nanotube-Reinforced Hydroxyapatite Doped with Silver and Silver-Core Selenium-Shell Nanoparticles: Synthesis, Characterization, and Biological Activity.Nanomaterials (Basel, Switzerland) · 2025Article
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- Comparative In Vitro Dissolution Assessment of Calcined and Uncalcined Hydroxyapatite Using Differences in Bioresorbability and Biomineralization.International journal of molecular sciences · 2024Article
- Interpretable Machine Learning Methods for Monitoring Polymer Degradation in Extrusion of Polylactic Acid.Polymers · 2023Article
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Production of biocompatible composite scaffolds shifts towards additive manufacturing where thermoplastic biodegradable polymers such as poly(lactic acid) (PLA) are used as matrices. Differences between industrial- and medical-grade polymers are often overlooked although they may affect properties and degradation behaviour as significantly as the filler addition. In the present research, composite films based on medical-grade PLA and biogenic hydroxyapatite (HAp) with 0, 10, and 20 wt.% of HAp were prepared by solvent casting technique. The degradation of composites incubated in phosphate-buffered saline solution (PBS) at 37 °C after 10 weeks showed that the higher HAp content slowed down the hydrolytic PLA degradation and improved its thermal stability. Morphological nonuniformity after degradation was indicated by the different glass transition temperatures (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.