Evidence map›Paper›PMID 36987220›Full record

ArticlePolymers2023

Immobilization and Release of Platelet-Rich Plasma from Modified Nanofibers Studied by Advanced X-ray Photoelectron Spectroscopy Analyses.

Anton M Manakhov, Elizaveta S Permyakova, Anastasiya O Solovieva, Natalya A Sitnikova, Philipp V Kiryukhantsev-Korneev, Anton S Konopatsky, Dmitry V Shtansky

Open access · goldAbstract read
In one paragraph

Article in Polymers, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anton M ManakhovResearch Institute of Clinical and Experimental Lymphology-Branch of the ICG SB RAS, 2 Timakova St., 630060 Novosibirsk, Russia.ORCID 0000-0003-4517-1682
Elizaveta S PermyakovaResearch Institute of Clinical and Experimental Lymphology-Branch of the ICG SB RAS, 2 Timakova St., 630060 Novosibirsk, Russia.ORCID 0000-0003-2581-0803
Anastasiya O SolovievaResearch Institute of Clinical and Experimental Lymphology-Branch of the ICG SB RAS, 2 Timakova St., 630060 Novosibirsk, Russia.ORCID 0000-0002-7740-8456
Natalya A SitnikovaResearch Institute of Clinical and Experimental Lymphology-Branch of the ICG SB RAS, 2 Timakova St., 630060 Novosibirsk, Russia.ORCID 0000-0002-8226-8996
Philipp V Kiryukhantsev-KorneevNational University of Science and Technology "MISiS", Leninsky Prospekt 4, 119049 Moscow, Russia.ORCID 0000-0003-1635-4746
Anton S KonopatskyNational University of Science and Technology "MISiS", Leninsky Prospekt 4, 119049 Moscow, Russia.ORCID 0000-0002-2597-6611
Dmitry V ShtanskyNational University of Science and Technology "MISiS", Leninsky Prospekt 4, 119049 Moscow, Russia.ORCID 0000-0001-7304-2461
National University of Science and Technology · RUSiberian Branch of the Russian Academy of Sciences · RU

Funding

Russian Science Foundation 18-75-10057Strategic Academic Leadership Program "Priority 2030" at NUST «MISiS Biomedical materials and bioengineering
6 · The paper itself

Abstract

Platelet-rich Plasma (PRP) is an ensemble of growth factors, extracellular matrix components, and proteoglycans that are naturally balanced in the human body. In this study, the immobilization and release of PRP component nanofiber surfaces modified by plasma treatment in a gas discharge have been investigated for the first time. The plasma-treated polycaprolactone (PCL) nanofibers were utilized as substrates for the immobilization of PRP, and the amount of PRP immobilized was assessed by fitting a specific X-ray Photoelectron Spectroscopy (XPS) curve to the elemental composition changes. The release of PRP was then revealed by measuring the XPS after soaking nanofibers containing immobilized PRP in buffers of varying pHs (4.8; 7.4; 8.1). Our investigations have proven that the immobilized PRP would continue to cover approximately fifty percent of the surface after eight days.

Indexed as

immobilizationnanofibersplatelet-rich plasmasurface chemistryXPS

Identifiers

PMID36987220
PMCPMC10056793
OpenAlexW4324156262

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.