Evidence map›Paper›PMID 36986860›Full record

ArticlePharmaceutics2023

Coating of SPIONs with a Cysteine-Decorated Copolyester: A Possible Novel Nanoplatform for Enzymatic Release.

Jeovandro Maria Beltrame, Brena Beatriz Pereira Ribeiro, Camila Guindani, Graziâni Candiotto, Karina Bettega Felipe, Rodrigo Lucas, Alexandre D'Agostini Zottis, Eduardo Isoppo, Claudia Sayer, Pedro Henrique Hermes de Araújo

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 1 country.

Jeovandro Maria BeltrameDepartment of Chemical Engineering and Food Engineering, Federal University of Santa Catarina (EQA/UFSC), Florianópolis 88040-900, SC, Brazil.
Brena Beatriz Pereira RibeiroDepartment of Chemical Engineering and Food Engineering, Federal University of Santa Catarina (EQA/UFSC), Florianópolis 88040-900, SC, Brazil.ORCID 0009-0003-4681-2565
Camila GuindaniChemical Engineering Program, COPPE, Federal University of Rio de Janeiro (PEQ/COPPE/UFRJ), Rio de Janeiro 21941-972, RJ, Brazil.ORCID 0000-0002-6571-2127
Graziâni CandiottoInstitute of Physics, Federal University of Rio de Janeiro, Rio de Janeiro 21941-909, RJ, Brazil.ORCID 0000-0001-6755-660X
Karina Bettega FelipeDepartment of Clinic Analysis, Federal University of Paraná DAC/UFPR, Curitiba 80.210-170, PR, Brazil.
Rodrigo LucasFoundation Osvaldo Cruz (FIOCRUZ), Curitiba 81350-010, PR, Brazil.
Alexandre D'Agostini ZottisAcademic Department of Health and Services, NANOTEC Group, Federal Institute of Santa Catarina, Florianópolis 88020-300, SC, Brazil.
Eduardo IsoppoCentral Laboratory of Electron Microscopy, Federal University of Santa Catarina, LCME/UFSC, Florianópolis 88040-900, SC, Brazil.
Claudia SayerDepartment of Chemical Engineering and Food Engineering, Federal University of Santa Catarina (EQA/UFSC), Florianópolis 88040-900, SC, Brazil.ORCID 0000-0003-1044-2905
Pedro Henrique Hermes de AraújoDepartment of Chemical Engineering and Food Engineering, Federal University of Santa Catarina (EQA/UFSC), Florianópolis 88040-900, SC, Brazil.ORCID 0000-0001-5905-0158
Universidade Federal de Santa Catarina · BRUniversidade Federal do Rio de Janeiro · BRFundação Oswaldo Cruz · BRInstituto Federal de Educação, Ciência e Tecnologia de Santa Catarina · BRUniversidade Federal do Paraná · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior 88887.310560/2018-00Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro E-26/201.911/2020, E-26/201.912/2020, E-26/200.627/2022 and E-26/210.391/2022Fundação de Amparo à Pesquisa e Inovação do Estado de Santa Catarina IFS2020201000004National Council for Scientific and Technological Development 406078/2018-1
6 · The paper itself

Abstract

Superparamagnetic iron oxide nanoparticles (SPIONs) have their use approved for the diagnosis/treatment of malignant tumors and can be metabolized by the organism. To prevent embolism caused by these nanoparticles, they need to be coated with biocompatible and non-cytotoxic materials. Here, we synthesized an unsaturated and biocompatible copolyester, poly (globalide-

Indexed as

and enzymatic releasebioconjugationcopolyestercysteineSPION

Identifiers

PMID36986860
PMCPMC10058032
OpenAlexW4327952006

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.