Evidence map›Paper›PMID 36986853›Full record

ArticlePharmaceutics2023

The Bioactivity of Xylene, Pyridine, and Pyrazole Aza Macrocycles against Three Representative

Álvaro Martín-Montes, Álvaro Martínez-Camarena, Alberto Lopera, Irene Bonastre-Sabater, M Paz Clares, Begoña Verdejo, Enrique García-España, Clotilde Marín

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Anti-Molecules (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Álvaro Martín-MontesDepartamento de Parasitología, Instituto de Investigación Biosanitaria (IBS. Granada), Hospitales Universitarios de Granada, Universidad de Granada, Severo Ochoa s/n, 18071 Granada, Spain.ORCID 0000-0001-7611-9014
Álvaro Martínez-CamarenaInstituto de Ciencia Molecular (ICMol), Universidad de Valencia, C/Catedrático José Beltrán 2, 46980 Paterna, Spain.ORCID 0000-0001-9910-6961
Alberto LoperaInstituto de Ciencia Molecular (ICMol), Universidad de Valencia, C/Catedrático José Beltrán 2, 46980 Paterna, Spain.
Irene Bonastre-SabaterInstituto de Ciencia Molecular (ICMol), Universidad de Valencia, C/Catedrático José Beltrán 2, 46980 Paterna, Spain.
M Paz ClaresInstituto de Ciencia Molecular (ICMol), Universidad de Valencia, C/Catedrático José Beltrán 2, 46980 Paterna, Spain.
Begoña VerdejoInstituto de Ciencia Molecular (ICMol), Universidad de Valencia, C/Catedrático José Beltrán 2, 46980 Paterna, Spain.ORCID 0000-0003-3022-1835
Enrique García-EspañaInstituto de Ciencia Molecular (ICMol), Universidad de Valencia, C/Catedrático José Beltrán 2, 46980 Paterna, Spain.
Clotilde MarínDepartamento de Parasitología, Instituto de Investigación Biosanitaria (IBS. Granada), Hospitales Universitarios de Granada, Universidad de Granada, Severo Ochoa s/n, 18071 Granada, Spain.ORCID 0000-0002-4316-2742
Universitat de València · ESUniversidad de Granada · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the urgent need for finding effective and free of secondary effect treatments for every clinical form of Leishmaniasis, a series of synthetic xylene, pyridine and, pyrazole azamacrocycles were tested against three

Indexed as

chemotherapyLeishmaniamacrocyclesmechanism of actionpyrazolepyridineSOD inhibition

Identifiers

PMID36986853
PMCPMC10059905
OpenAlexW4327953213

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.