ReviewPharmaceutics2023
Antimicrobial Nano-Zinc Oxide Biocomposites for Wound Healing Applications: A Review.
Review in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 1 synthesis or guideline pooled it, 151 citations in OpenAlex.
- Natural Bioactive-Based Advanced Wound Dressings for Diabetic Wound Healing: A Systematic Review of Emerging Biomaterial Platforms.International journal of nanomedicine · 2026Pooled it
- Dodonaea viscosa-mediated zinc oxide nanoparticles exhibit antibacterial, anti-biofilm, and anti-virulence activity against methicillin-resistant Staphylococcus aureus.International microbiology : the official journal of the Spanish Society for Microbiology · 2026Article
- Enzyme-Responsive Composite Hydrogel Coating Containing Nano-HA/Nano-ZnO with Pro-Osteogenic and Anti-Osteoclastic Properties.Macromolecular bioscience · 2026Article
- Evaluation of Wound Healing in Wistar Rat Model via Curcumin-Functionalized Copper Nanoparticle Ointment.Applied biochemistry and biotechnology · 2026Article
- Biopolymer-mediated metallic nanomaterials: recent advancements, current challenges and future outlooks.RSC advances · 2026Review
- Data-Driven Engineering of Antimicrobial Nanomaterials for Food Safety and Biomedical Systems.Nanomaterials (Basel, Switzerland) · 2026Review
- Antimicrobial Systems Based on Essential Oils Advanced by Zinc Oxide Nanoparticles.ACS pharmacology & translational science · 2026Review
- Targeting Biofilms in Chronic Wounds: Emerging Strategies with Antimicrobial Nanocomposites.Journal of functional biomaterials · 2026Review
- Functional xanthan gum-based ZnO nanocomposite for antimicrobial applications: synthesis, properties, and performance evaluation.BMC chemistry · 2026Article
- The effects of platelet rich plasma and zinc oxide nanoparticle on skin wound healing in dogs.Scientific reports · 2026Article
- Medical Fabrics with Non-Antibiotic, Supramolecular Antimicrobial Coatings: A Preventive Approach to Combat Biofilm Formation and Bacterial Dissemination.Advanced healthcare materials · 2026Article
- Development and In Vitro Characterization of Light Responsive Zinc-Based Nanoparticles Embedded in Collagen Sheets Intended for Wound Care Oriented Applications.Macromolecular bioscience · 2026Article
- Green synthesis of ZnO nanoparticles using Citrus sinensis peel: optimizing volume ratios for enhanced antibacterial and banana preservation activities.BMC biotechnology · 2026Article
- Quantum modeling of Stokes-Induced Stark Fields in quercetin-ZnO nanohybrids for bias-free bioelectric repair of chronic diabetic foot ulcers.Journal of molecular modeling · 2026Article
- Electrospun PVA Nanofibers Co-Loaded with Atorvastatin and Zinc Oxide for Antibacterial and In Vitro Wound Healing Applications.Biomedicines · 2026Article
- Development of a banana stem fiber-reinforced chitosan-xanthan gum wound healing patch loaded with Tridax procumbens extract for biomedical applications.Scientific reports · 2026Article
- Article
- Synthesis of novel nano composite based on silicone/HEMA/AAm/ZnO as an efficient wound dressing: physicochemical and biological study.Designed monomers and polymers · 2026Article
- Preclinical Evaluation of a Zinc Oxide Nanoparticle-Loaded Amniotic Membrane as a Bioactive Scaffold for Partial-Thickness Burn Healing in Rats.BioMed research international · 2026Article
- Exploring the potential of MXenes in advanced energy, environmental, and biomedical applications.RSC advances · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic wounds are a major concern for global health, affecting millions of individuals worldwide. As their occurrence is correlated with age and age-related comorbidities, their incidence in the population is set to increase in the forthcoming years. This burden is further worsened by the rise of antimicrobial resistance (AMR), which causes wound infections that are increasingly hard to treat with current antibiotics. Antimicrobial bionanocomposites are an emerging class of materials that combine the biocompatibility and tissue-mimicking properties of biomacromolecules with the antimicrobial activity of metal or metal oxide nanoparticles. Among these nanostructured agents, zinc oxide (ZnO) is one of the most promising for its microbicidal effects and its anti-inflammatory properties, and as a source of essential zinc ions. This review analyses the most recent developments in the field of nano-ZnO-bionanocomposite (nZnO-BNC) materials-mainly in the form of films, but also hydrogel or electrospun bandages-from the different preparation techniques to their properties and antibacterial and wound-healing performances. The effect of nanostructured ZnO on the mechanical, water and gas barrier, swelling, optical, thermal, water affinity, and drug-release properties are examined and linked to the preparation methods. Antimicrobial assays over a wide range of bacterial strains are extensively surveyed, and wound-healing studies are finally considered to provide a comprehensive assessment framework. While early results are promising, a systematic and standardised testing procedure for the comparison of antibacterial properties is still lacking, partly because of a not-yet fully understood antimicrobial mechanism. This work, therefore, allowed, on one hand, the determination of the best strategies for the design, engineering, and application of n-ZnO-BNC, and, on the other hand, the identification of the current challenges and opportunities for future research.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.