Evidence map›Paper›PMID 36986820›Full record

ArticlePharmaceutics2023

A New Productive Approach and Formulative Optimization for Curcumin Nanoliposomal Delivery Systems.

Raffaella De Piano, Diego Caccavo, Gaetano Lamberti, Katrien Remaut, Hanne Seynaeve, Anna Angela Barba

Abstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Raffaella De PianoDipartimento di Ingegneria Industriale, Università degli Studi di Salerno, Via Giovanni Paolo II n.132, 84084 Fisciano, Italy.
Diego CaccavoDipartimento di Ingegneria Industriale, Università degli Studi di Salerno, Via Giovanni Paolo II n.132, 84084 Fisciano, Italy.ORCID 0000-0003-3102-6281
Gaetano LambertiDipartimento di Ingegneria Industriale, Università degli Studi di Salerno, Via Giovanni Paolo II n.132, 84084 Fisciano, Italy.ORCID 0000-0003-1689-6887
Katrien RemautDepartment of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, 9000 Gent, Belgium.ORCID 0000-0002-2244-1339
Hanne SeynaeveDepartment of Pharmaceutics, Ghent University, Ottergemsesteenweg 460, 9000 Gent, Belgium.
Anna Angela BarbaEng4Life srl, University Spin-Off, Via Circumvallazione n.39, 83100 Avellino, Italy.ORCID 0000-0003-3144-4598

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The use of natural resources and the enhancing of technologies are outlining the strategies of modern scientific-technological research for sustainable health products manufacturing. In this context, the novel simil-microfluidic technology, a mild production methodology, is exploited to produce liposomal curcumin as potential powerful dosage system for cancer therapies and for nutraceutical purposes. Through simil-microfluidic technology, based on interdiffusion phenomena of a lipid-ethanol phase in an aqueous flow, massive productions of liposomes at nanometric scale can be obtained. In this work, studies on liposomal production with useful curcumin loads were performed. In particular, process issues (curcumin aggregations) were elucidated and formulation optimization for curcumin load was performed. The main achieved result has been the definition of operative conditions for nanoliposomal curcumin production with interesting loads and encapsulation efficiencies.

Indexed as

anticancerantioxidant activitycurcuminnanoliposomesnanotechnologiesnutraceuticalssimil-microfluidic technology

Identifiers

PMID36986820
PMCPMC10051773

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.