Evidence map›Paper›PMID 36986707›Full record

ReviewPharmaceutics2023

Lentiviral Vectors as a Vaccine Platform against Infectious Diseases.

Kirill Nemirov, Maryline Bourgine, François Anna, Yu Wei, Pierre Charneau, Laleh Majlessi

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
7.8field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. An updated review of Zika virus vaccine development.Clinical and experimental vaccine research · 2025
    Review
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Review
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  18. Article
  19. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Kirill NemirovPasteur-TheraVectys Joint Lab, Institut Pasteur, Université de Paris, 28 rue du Dr Roux, CEDEX 15, 75724 Paris, France.
Maryline BourginePasteur-TheraVectys Joint Lab, Institut Pasteur, Université de Paris, 28 rue du Dr Roux, CEDEX 15, 75724 Paris, France.ORCID 0000-0002-8850-8073
François AnnaPasteur-TheraVectys Joint Lab, Institut Pasteur, Université de Paris, 28 rue du Dr Roux, CEDEX 15, 75724 Paris, France.
Yu WeiPasteur-TheraVectys Joint Lab, Institut Pasteur, Université de Paris, 28 rue du Dr Roux, CEDEX 15, 75724 Paris, France.
Pierre CharneauPasteur-TheraVectys Joint Lab, Institut Pasteur, Université de Paris, 28 rue du Dr Roux, CEDEX 15, 75724 Paris, France.
Laleh MajlessiPasteur-TheraVectys Joint Lab, Institut Pasteur, Université de Paris, 28 rue du Dr Roux, CEDEX 15, 75724 Paris, France.
Institut Pasteur · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lentiviral vectors are among the most effective viral vectors for vaccination. In clear contrast to the reference adenoviral vectors, lentiviral vectors have a high potential for transducing dendritic cells in vivo. Within these cells, which are the most efficient at activating naive T cells, lentiviral vectors induce endogenous expression of transgenic antigens that directly access antigen presentation pathways without the need for external antigen capture or cross-presentation. Lentiviral vectors induce strong, robust, and long-lasting humoral, CD8

Indexed as

antigen presentationinflammationlentiviral vaccine vectorsmajor histocompatibility complexpre-existing anti-vector immunityT-cell vaccinestropism for dendritic cells

Identifiers

PMID36986707
PMCPMC10053212
OpenAlexW4323313260

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.