Evidence map›Paper›PMID 36986669›Full record

ReviewPharmaceutics2023

Relevance of the Extraction Stage on the Anti-Inflammatory Action of Fucoidans.

Noelia Flórez-Fernández, Carlos Vaamonde-García, Maria Dolores Torres, Manuela Buján, Alexandra Muíños, Antonio Muiños, María J Lamas-Vázquez, Rosa Meijide-Faílde, Francisco J Blanco, Herminia Domínguez

Abstract readReview
In one paragraph

Review in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Molecular Basis and Mechanistic Insights intoPlants (Basel, Switzerland) · 2026
    Review
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Noelia Flórez-FernándezCINBIO, Departamento de Ingeniería Química, Campus Ourense, Universidade de Vigo, 32004 Ourense, Spain.ORCID 0000-0002-2666-2315
Carlos Vaamonde-GarcíaGrupo de Investigación de Reumatología y Salud (GIR-S), Departamento de Biología, Facultad de Ciencias, CICA-Centro Interdisciplinar de Química y Biología, INIBIC-Sergas, Universidade da Coruña, Campus da Zapateira, 15011 A Coruña, Spain.ORCID 0000-0001-8658-5502
Maria Dolores TorresCINBIO, Departamento de Ingeniería Química, Campus Ourense, Universidade de Vigo, 32004 Ourense, Spain.ORCID 0000-0001-6811-1290
Manuela BujánPortomuíños, Polígono Industrial, Rúa Acebedo, Parcela 14, Cerceda, 15185 A Coruña, Spain.
Alexandra MuíñosPortomuíños, Polígono Industrial, Rúa Acebedo, Parcela 14, Cerceda, 15185 A Coruña, Spain.
Antonio MuiñosPortomuíños, Polígono Industrial, Rúa Acebedo, Parcela 14, Cerceda, 15185 A Coruña, Spain.
María J Lamas-VázquezGrupo de Investigación de Reumatología y Salud (GIR-S), Departamento de Biología, Facultad de Ciencias, CICA-Centro Interdisciplinar de Química y Biología, INIBIC-Sergas, Universidade da Coruña, Campus da Zapateira, 15011 A Coruña, Spain.
Rosa Meijide-FaíldeGrupo de Terapia Celular y Medicina Regenerativa, Universidade da Coruña, CICA-Centro Interdisciplinar de Química y Biología, Complexo Hospitalario Universitario A Coruña, Campus Oza, 15006 A Coruña, Spain.ORCID 0000-0001-8516-9419
Francisco J BlancoGrupo de Investigación de Reumatología y Salud (GIR-S), Departamento de Fisioterapia, Medicina y Ciencias Biomédicas, Facultad de Fisioterapia, CICA-Centro Interdisciplinar de Química y Biología, INIBIC-Sergas, Universidade da Coruña, Campus de Oza, 15006 A Coruña, Spain.
Herminia DomínguezCINBIO, Departamento de Ingeniería Química, Campus Ourense, Universidade de Vigo, 32004 Ourense, Spain.ORCID 0000-0002-6475-3242

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The anti-inflammatory action of fucoidans is well known, based on both in vitro and some in vivo studies. The other biological properties of these compounds, their lack of toxicity, and the possibility of obtaining them from a widely distributed and renewable source, makes them attractive novel bioactives. However, fucoidans' heterogeneity and variability in composition, structure, and properties depending on seaweed species, biotic and abiotic factors and processing conditions, especially during extraction and purification stages, make it difficult for standardization. A review of the available technologies, including those based on intensification strategies, and their influence on fucoidan composition, structure, and anti-inflammatory potential of crude extracts and fractions is presented.

Indexed as

brown seaweedextractioninflammationsulphated polysaccharides

Identifiers

PMID36986669
PMCPMC10058023

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.