Evidence map›Paper›PMID 36986652›Full record

ArticlePharmaceutics2023

Influence of the Topology of Poly(L-Cysteine) on the Self-Assembly, Encapsulation and Release Profile of Doxorubicin on Dual-Responsive Hybrid Polypeptides.

Dimitra Stavroulaki, Iro Kyroglou, Dimitrios Skourtis, Varvara Athanasiou, Pandora Thimi, Sosanna Sofianopoulou, Diana Kazaryan, Panagiota G Fragouli, Andromahi Labrianidou, Konstantinos Dimas and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 2 countries.

Dimitra StavroulakiIndustrial Chemistry Laboratory, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, Zografou, GR-15771 Athens, Greece.
Iro KyroglouIndustrial Chemistry Laboratory, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, Zografou, GR-15771 Athens, Greece.
Dimitrios SkourtisIndustrial Chemistry Laboratory, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, Zografou, GR-15771 Athens, Greece.ORCID 0000-0003-2709-6551
Varvara AthanasiouIndustrial Chemistry Laboratory, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, Zografou, GR-15771 Athens, Greece.
Pandora ThimiIndustrial Chemistry Laboratory, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, Zografou, GR-15771 Athens, Greece.
Sosanna SofianopoulouHellenic Police Headquarters, Forensic Science Division, Chemical and Physical Examinations Department, GR-10442 Athens, Greece.
Diana KazaryanIndustrial Chemistry Laboratory, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, Zografou, GR-15771 Athens, Greece.
Panagiota G FragouliDIDPE, Dyeing, Finishing, Dyestuffs and Advanced Polymers Laboratory, University of West Attica, 250 Thevon Street, GR-12241 Athens, Greece.
Andromahi LabrianidouLaboratory of Pharmacology, Faculty of Medicine, University of Thessaly, Viopolis, GR-41500 Larissa, Greece.
Konstantinos DimasLaboratory of Pharmacology, Faculty of Medicine, University of Thessaly, Viopolis, GR-41500 Larissa, Greece.ORCID 0000-0001-7481-9148
Georgios PatiasDepartment of Chemistry, University of Warwick, Gibbet Hill, Coventry CV4 7AL, UK.
David M HaddletonDepartment of Chemistry, University of Warwick, Gibbet Hill, Coventry CV4 7AL, UK.
Hermis IatrouIndustrial Chemistry Laboratory, Department of Chemistry, National and Kapodistrian University of Athens, Panepistimiopolis, Zografou, GR-15771 Athens, Greece.ORCID 0000-0001-9358-0769
National and Kapodistrian University of Athens · GRUniversity of Thessaly · GRUniversity of Warwick · GBHellenic Police Academy · GRUniversity of West Attica · GR

Funding

Hellenic Foundation for Research and Innovation (H.F.R.I.) 2nd Call for H.F.R.I. Research Projects to support Faculty Members & Researchers" (Project Number: 2762)
6 · The paper itself

Abstract

Τhe synthesis of a series of novel hybrid block copolypeptides based on poly(ethylene oxide) (PEO), poly(l-histidine) (PHis) and poly(l-cysteine) (PCys) is presented. The synthesis of the terpolymers was achieved through a ring-opening polymerization (ROP) of the corresponding protected

Indexed as

cancerdoxorubicindrug deliverynanoparticlespolypeptidestopology of poly-l-cystein

Identifiers

PMID36986652
PMCPMC10055909
OpenAlexW4322629136

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.