Evidence map›Paper›PMID 36986609›Full record

ArticlePharmaceutics2023

Electrospun Naringin-Loaded Fibers for Preventing Scar Formation during Wound Healing.

Erika M Tottoli, Laura Benedetti, Enrica Chiesa, Silvia Pisani, Giovanna Bruni, Ida Genta, Bice Conti, Gabriele Ceccarelli, Rossella Dorati

Open access · goldAbstract read
In one paragraph

Article in Pharmaceutics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Myricetin Nanofibers as Amorphous Delivery System.Pharmaceuticals (Basel, Switzerland) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Erika M TottoliDepartment of Drug Sciences, University of Pavia, 27100 Pavia, Italy.
Laura BenedettiDepartment of Public Health, Experimental Medicine and Forensic, University of Pavia, 27100 Pavia, Italy.
Enrica ChiesaDepartment of Drug Sciences, University of Pavia, 27100 Pavia, Italy.
Silvia PisaniDepartment of Otolaryngology, IRCCS Policlinico S. Matteo, 27100 Pavia, Italy.ORCID 0000-0002-5396-1601
Giovanna BruniDepartment of Chemistry, Physical-Chemistry Section, University of Pavia, Via Taramelli 16, 27100 Pavia, Italy.ORCID 0000-0003-1958-2998
Ida GentaDepartment of Drug Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0001-5710-0588
Bice ContiDepartment of Drug Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-0034-2815
Gabriele CeccarelliDepartment of Public Health, Experimental Medicine and Forensic, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0002-8576-694X
Rossella DoratiDepartment of Drug Sciences, University of Pavia, 27100 Pavia, Italy.ORCID 0000-0001-5774-9547
University of Pavia · ITPoliclinico San Matteo Fondazione · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hypertrophic scars (HTSs) are aberrant structures that develop where skin is injured complexly and represent the result of a chronic inflammation as a healing response. To date, there is no satisfactory prevention option for HTSs, which is due to the complexity of multiple mechanisms behind the formation of these structures. The present work aimed to propose Biofiber (Biodegradable fiber), an advanced textured electrospun dressing, as a suitable solution for HTS formation in complex wounds. Biofiber has been designed as a 3-day long-term treatment to protect the healing environment and enhance wound care practices. Its textured matrix consists of homogeneous and well-interconnected Poly-L-lactide-co-poly-ε-caprolactone (PLA-PCL) electrospun fibers (size 3.825 ± 1.12 µm) loaded with Naringin (NG, 2.0%

Indexed as

complex woundselectrospinninghypertrophic scarwound healing

Identifiers

PMID36986609
PMCPMC10053957
OpenAlexW4321787409

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.