Evidence map›Paper›PMID 36986572›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

Pharmacological Profile of the Purinergic P2Y Receptors That Modulate, in Response to ADPβS, the Vasodepressor Sensory CGRPergic Outflow in Pithed Rats.

Alejandro D Miguel-Martínez, Juan Linares-Bedolla, Belinda Villanueva-Castillo, Kristian A Haanes, Antoinette MaassenVanDenBrink, Carlos M Villalón

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Alejandro D Miguel-MartínezDepartamento de Farmacobiología, Cinvestav-Coapa, Czda. de los Tenorios 235, Col. Granjas Coapa, Deleg. Tlalpan, Ciudad de Mexico C.P. 14330, Mexico.ORCID 0000-0001-5176-5466
Juan Linares-BedollaDepartamento de Farmacobiología, Cinvestav-Coapa, Czda. de los Tenorios 235, Col. Granjas Coapa, Deleg. Tlalpan, Ciudad de Mexico C.P. 14330, Mexico.ORCID 0000-0002-8968-8088
Belinda Villanueva-CastilloDepartamento de Farmacobiología, Cinvestav-Coapa, Czda. de los Tenorios 235, Col. Granjas Coapa, Deleg. Tlalpan, Ciudad de Mexico C.P. 14330, Mexico.ORCID 0000-0003-3516-8885
Kristian A HaanesDepartment of Clinical Experimental Research, Glostrup Research Institute, Copenhagen University Hospital-Rigshospitalet, Nordstjernevej 42, DK-2600 Glostrup, Denmark.ORCID 0000-0001-5182-8957
Antoinette MaassenVanDenBrinkDivision of Vascular Medicine and Pharmacology, Erasmus MC University Medical Center Rotterdam, P.O. Box 2040, 3000 CA Rotterdam, The Netherlands.ORCID 0000-0001-7176-126X
Carlos M VillalónDepartamento de Farmacobiología, Cinvestav-Coapa, Czda. de los Tenorios 235, Col. Granjas Coapa, Deleg. Tlalpan, Ciudad de Mexico C.P. 14330, Mexico.ORCID 0000-0003-4117-1343
Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional · MXErasmus MC · NLGlostrup Hospital · DK

Funding

Consejo Nacional de Ciencia y Tecnología 219707SEP Cinvestav Research Support Fund 50
6 · The paper itself

Abstract

Calcitonin gene-related peptide (CGRP), an endogenous neuropeptide released from perivascular sensory nerves, exerts a powerful vasodilatation. Interestingly, adenosine triphosphate (ATP) stimulates the release of CGRP by activation of prejunctional P2X

Indexed as

ADPβSglibenclamidepithed ratpurinergic receptorsvasodepressor sensory CGRPergic tone

Identifiers

PMID36986572
PMCPMC10056196
OpenAlexW4353069342

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.