Evidence map›Paper›PMID 36986521›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

SPECT Imaging with Tc-99m-Labeled HYNIC-FAPI-04 to Extend the Differential Time Window in Evaluating Tumor Fibrosis.

Xiu Luo, Zhe Zhang, Chao Cheng, Tao Wang, Danzhou Fang, Changjing Zuo, Gengbiao Yuan, Rou Li, Xiao Li

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06753513 (Clinical Application of 99mTc-FDPH46 SPECT/CT Imaging in Malignant Solid Tumor), which is not on this map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06753513 not yet recruitingnot on this mapstarted 2024, after this paper: background citation

Clinical Application of 99mTc-FDPH46 SPECT/CT Imaging in Malignant Solid Tumor: a Prospective Exploratory Study

TypeobservationalSponsorZhejiang UniversityRan2024 to 2026Enrolled20ConditionsMalignant Tumors, Solid Tumor MalignancyArms99mTc-FDPH46 SPECT/CT Imaging
3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Comparative Evaluation of [Molecular imaging and biology · 2026
    Article
  2. Review
  3. Review
  4. EJNMMI radiopharmacy and chemistry · 2024
    Review
  5. Pharmaceutics · 2024
    Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Xiu LuoDepartment of Nuclear Medicine, Shanghai Changhai Hospital, Shanghai 200433, China.
Zhe ZhangDepartment of Nuclear Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.ORCID 0009-0008-2285-7650
Chao ChengDepartment of Nuclear Medicine, Shanghai Changhai Hospital, Shanghai 200433, China.
Tao WangDepartment of Nuclear Medicine, Shanghai Changhai Hospital, Shanghai 200433, China.
Danzhou FangDepartment of Nuclear Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Changjing ZuoDepartment of Nuclear Medicine, Shanghai Changhai Hospital, Shanghai 200433, China.
Gengbiao YuanDepartment of Nuclear Medicine, The Second Affiliated Hospital of Chongqing Medical University, Chongqing 400010, China.
Rou LiDepartment of Nuclear Medicine, Shanghai Changhai Hospital, Shanghai 200433, China.
Xiao LiDepartment of Nuclear Medicine, Shanghai Changhai Hospital, Shanghai 200433, China.
Second Military Medical University · CNDalian Medical University · CN

Funding

Changjing Zuo 2022JC004, 82272040, GH145-22, 2019YPT002 and 2020YPT002
6 · The paper itself

Abstract

The so-far used Ga-68- or F-18-labelled tracers are of a relative short time window in differentiating tumor fibrosis. SPECT applicable imaging probe,

Indexed as

99mTc-HYNIC-FAPI-04differential time windowFAPI-04FAP inhibitorfibroblast activating proteintumor fibrosis

Identifiers

PMID36986521
PMCPMC10051245
OpenAlexW4324064551

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.