Evidence map›Paper›PMID 36986462›Full record

ReviewPharmaceuticals (Basel, Switzerland)2023

Encapsulation: A Strategy to Deliver Therapeutics and Bioactive Compounds?

Iveta Klojdová, Tomáš Milota, Jitka Smetanová, Constantinos Stathopoulos

Open access · goldAbstract readReview
In one paragraph

Review in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
21.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 109 citations in OpenAlex.

  1. Review
  2. Review
  3. Natural Pigments and Cyclodextrins: Overview on a Synergistic Approach to Encapsulation.Comprehensive reviews in food science and food safety · 2026
    Review
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Review
  13. Review
  14. Article
  15. Hepatorenal protective role of encapsulatedJournal of advanced veterinary and animal research · 2026
    Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Iveta KlojdováDRIFT-FOOD, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, 165 21 Prague, Czech Republic.ORCID 0000-0002-6524-0916
Tomáš MilotaDepartment of Immunology, Second Faculty of Medicine Charles University and Motol University Hospital, 150 06 Prague, Czech Republic.ORCID 0000-0003-2105-3462
Jitka SmetanováDepartment of Immunology, Second Faculty of Medicine Charles University and Motol University Hospital, 150 06 Prague, Czech Republic.
Constantinos StathopoulosDRIFT-FOOD, Faculty of Agrobiology, Food and Natural Resources, Czech University of Life Sciences Prague, 165 21 Prague, Czech Republic.ORCID 0000-0001-9241-7580
Charles University · CZCzech University of Life Sciences Prague · CZ

Funding

European Union European Union's Horizon 2020 Research and Innovation Program under grant agreement No 952594 (ERA Chair project DRIFT-FOOD)Ministry of Health Czech Republic Czech Health Research Council, project no. NU22-05-00402
6 · The paper itself

Abstract

There is a growing demand for efficient medical therapies without undesired side effects that limit their application. Targeted therapies such as deliveries of pharmacologically active compounds to a specific site of action in the human body are still a big challenge. Encapsulation is an effective tool for targeted deliveries of drugs and sensitive compounds. It has been exploited as a technique that can manage the required distribution, action and metabolism of encapsulated agents. Food supplements or functional foods containing encapsulated probiotics, vitamins, minerals or extracts are often part of therapies and currently also a consumption trend. For effective encapsulation, optimal manufacturing has to be ensured. Thus, there is a trend to develop new (or modify existing) encapsulation methods. The most-used encapsulation approaches are based on barriers made from (bio)polymers, liposomes, multiple emulsions, etc. In this paper, recent advances in the use of encapsulation in the fields of medicine, food supplements and functional foods are highlighted, with emphasis on its benefits within targeted and supportive treatments. We have focused on a comprehensive overview of encapsulation options in the field of medicine and functional preparations that complement them with their positive effects on human health.

Indexed as

drugsencapsulationfood supplementsfunctional foodsimmunogenicitytargeted distribution of therapeuticstargeted therapyvaccines

Identifiers

PMID36986462
PMCPMC10053789
OpenAlexW4322629346

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.