Evidence map›Paper›PMID 36986448›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

Anti-Inflammatory, Antioxidant, and WAT/BAT-Conversion Stimulation Induced by Novel PPAR Ligands: Results from Ex Vivo and In Vitro Studies.

Lucia Recinella, Barbara De Filippis, Maria Loreta Libero, Alessandra Ammazzalorso, Annalisa Chiavaroli, Giustino Orlando, Claudio Ferrante, Letizia Giampietro, Serena Veschi, Alessandro Cama and 6 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
  3. PMHeliyon · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 2 institutions in 1 country.

Lucia RecinellaDepartment of Pharmacy, G. d'Annunzio University, 66100 Chieti, Italy.
Barbara De FilippisDepartment of Pharmacy, G. d'Annunzio University, 66100 Chieti, Italy.ORCID 0000-0001-7718-5814
Maria Loreta LiberoDepartment of Pharmacy, G. d'Annunzio University, 66100 Chieti, Italy.ORCID 0000-0002-8133-5691
Alessandra AmmazzalorsoDepartment of Pharmacy, G. d'Annunzio University, 66100 Chieti, Italy.ORCID 0000-0003-4369-1772
Annalisa ChiavaroliDepartment of Pharmacy, G. d'Annunzio University, 66100 Chieti, Italy.ORCID 0000-0002-3399-967X
Giustino OrlandoDepartment of Pharmacy, G. d'Annunzio University, 66100 Chieti, Italy.
Claudio FerranteDepartment of Pharmacy, G. d'Annunzio University, 66100 Chieti, Italy.ORCID 0000-0001-9431-9407
Letizia GiampietroDepartment of Pharmacy, G. d'Annunzio University, 66100 Chieti, Italy.ORCID 0000-0002-8483-1885
Serena VeschiDepartment of Pharmacy, G. d'Annunzio University, 66100 Chieti, Italy.ORCID 0000-0003-0450-9210
Alessandro CamaDepartment of Pharmacy, G. d'Annunzio University, 66100 Chieti, Italy.ORCID 0000-0003-3647-1368
Federica ManninoDepartment of Clinical and Experimental Medicine, University of Messina, 98122 Messina, Italy.
Irene GasparoDepartment of Clinical and Experimental Medicine, University of Messina, 98122 Messina, Italy.
Alessandra BittoDepartment of Clinical and Experimental Medicine, University of Messina, 98122 Messina, Italy.
Rosa AmorosoDepartment of Pharmacy, G. d'Annunzio University, 66100 Chieti, Italy.ORCID 0000-0002-8282-8535
Luigi BrunettiDepartment of Pharmacy, G. d'Annunzio University, 66100 Chieti, Italy.
Sheila LeoneDepartment of Pharmacy, G. d'Annunzio University, 66100 Chieti, Italy.ORCID 0000-0003-1291-550X
University of Chieti-Pescara · ITUniversity of Messina · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Activation of peroxisome proliferator-activated receptors (PPARs) not only regulates multiple metabolic pathways, but mediates various biological effects related to inflammation and oxidative stress. We investigated the effects of four new PPAR ligands containing a fibrate scaffold-the PPAR agonists (

Indexed as

adipose tissueobesityPPAR modulatorsUCP1

Identifiers

PMID36986448
PMCPMC10056895
OpenAlexW4322502731

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.