Evidence map›Paper›PMID 36986444›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

Structure-Based Virtual Screening of Furan-1,3,4-Oxadiazole Tethered

Ali Irfan, Shah Faisal, Sajjad Ahmad, Sami A Al-Hussain, Sadia Javed, Ameer Fawad Zahoor, Bushra Parveen, Magdi E A Zaki

Abstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Total Syntheses of Deuterated Drugs: A Comprehensive Review.Topics in current chemistry (Cham) · 2025
    Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Synthesis, molecular structure and urease inhibitory activity of novelSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ali IrfanDepartment of Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.ORCID 0000-0002-8977-3303
Shah FaisalDepartment of Chemistry, Islamia College University Peshawar, Peshawar 25120, Pakistan.ORCID 0000-0002-5105-6982
Sajjad AhmadDepartment of Health and Biological Sciences, Abasyn University, Peshawar 25000, Pakistan.ORCID 0000-0003-0754-1742
Sami A Al-HussainDepartment of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11623, Saudi Arabia.
Sadia JavedDepartment of Biochemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.ORCID 0000-0002-8233-5108
Ameer Fawad ZahoorDepartment of Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.ORCID 0000-0003-2127-8848
Bushra ParveenDepartment of Chemistry, Government College University Faisalabad, Faisalabad 38000, Pakistan.ORCID 0000-0002-4206-0277
Magdi E A ZakiDepartment of Chemistry, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh 11623, Saudi Arabia.ORCID 0000-0002-5643-9202

Funding

The authors thank the Deanship of Scientific Research at Imam Mohammad Ibn Saud Islamic University for funding this work through Research Group no. RG 21-09-77. Research Group no. RG 21-09-77.
6 · The paper itself

Abstract

Human tyrosinase (hTYR) is a key and rate-limiting enzyme along with human tyrosinase-related protein-1 (hTYRP1), which are among the most prominent targets of inhibiting hyper pigmentation and melanoma skin cancer. In the current in-silico computer-aided drug design (CADD) study, the structure-based screening of sixteen furan-1,3,4-oxadiazole tethered

Indexed as

furan-1,3,4-oxadiazolehTYRhTYRP1MD simulationsmelanogenesismolecular docking

Identifiers

PMID36986444
PMCPMC10059052

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.