Evidence map›Paper›PMID 36986443›Full record

ArticlePharmaceuticals (Basel, Switzerland)2023

Kaurenoic Acid Reduces Ongoing Chronic Constriction Injury-Induced Neuropathic Pain: Nitric Oxide Silencing of Dorsal Root Ganglia Neurons.

Tiago H Zaninelli, Sandra S Mizokami, Mariana M Bertozzi, Telma Saraiva-Santos, Felipe A Pinho-Ribeiro, Gabriele Inácio de Oliveira, Renata Streck, Eduardo J A Araújo, Nilton S Arakawa, Sergio M Borghi and 2 more

Open access · goldAbstract read
In one paragraph

Article in Pharmaceuticals (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Synthetic Derivatives of NaturalInternational journal of molecular sciences · 2024
    Article
  3. Frontiers in pharmacology · 2023
    Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Tiago H ZaninelliLaboratory of Pain, Inflammation, Neuropathy, and Cancer, Department of Pathology, Center of Biological Sciences, Londrina State University, Londrina 86057-970, Paraná, Brazil.ORCID 0000-0001-7233-477X
Sandra S MizokamiLaboratory of Pain, Inflammation, Neuropathy, and Cancer, Department of Pathology, Center of Biological Sciences, Londrina State University, Londrina 86057-970, Paraná, Brazil.ORCID 0000-0002-3002-2687
Mariana M BertozziLaboratory of Pain, Inflammation, Neuropathy, and Cancer, Department of Pathology, Center of Biological Sciences, Londrina State University, Londrina 86057-970, Paraná, Brazil.ORCID 0000-0002-0551-4313
Telma Saraiva-SantosLaboratory of Pain, Inflammation, Neuropathy, and Cancer, Department of Pathology, Center of Biological Sciences, Londrina State University, Londrina 86057-970, Paraná, Brazil.
Felipe A Pinho-RibeiroLaboratory of Pain, Inflammation, Neuropathy, and Cancer, Department of Pathology, Center of Biological Sciences, Londrina State University, Londrina 86057-970, Paraná, Brazil.
Gabriele Inácio de OliveiraDepartment of Pharmaceutical Sciences, Center of Health Sciences, Londrina State University, Londrina 86039-440, Paraná, Brazil.
Renata StreckDepartment of Histology, Londrina State University, Londrina 86057-970, Paraná, Brazil.
Eduardo J A AraújoDepartment of Histology, Londrina State University, Londrina 86057-970, Paraná, Brazil.
Nilton S ArakawaDepartment of Pharmaceutical Sciences, Center of Health Sciences, Londrina State University, Londrina 86039-440, Paraná, Brazil.
Sergio M BorghiLaboratory of Pain, Inflammation, Neuropathy, and Cancer, Department of Pathology, Center of Biological Sciences, Londrina State University, Londrina 86057-970, Paraná, Brazil.ORCID 0000-0002-6978-7505
Rubia CasagrandeDepartment of Pharmaceutical Sciences, Center of Health Sciences, Londrina State University, Londrina 86039-440, Paraná, Brazil.ORCID 0000-0002-2296-1668
Waldiceu A VerriLaboratory of Pain, Inflammation, Neuropathy, and Cancer, Department of Pathology, Center of Biological Sciences, Londrina State University, Londrina 86057-970, Paraná, Brazil.ORCID 0000-0003-2756-9283
Universidade Estadual de Londrina · BR

Funding

Coordenação de Aperfeicoamento de Pessoal de Nível Superior Finance code 001Fundação Araucária PPSUS grant agreement #041/2017; PRONEX grant agreement #014/2017Fundação Nacional de Desenvolvimento do Ensino Superior Particular #5301159National Council for Scientific and Technological Development (#405027/2021-4; #427946/2018-2; #309633/2021-4; #307852/2019-9
6 · The paper itself

Abstract

Kaurenoic acid (KA) is a diterpene extracted from

Indexed as

analgesiaCCIchronic constriction injurykaurenoic acidneuropathic painnitric oxidepotassium channelsSphagneticola trilobata

Identifiers

PMID36986443
PMCPMC10051686
OpenAlexW4321645652

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.