Evidence map›Paper›PMID 36986390›Full record

ReviewPathogens (Basel, Switzerland)2023

Role of Gut Microbiota in Breast Cancer and Drug Resistance.

Sathiyapriya Viswanathan, Sheetal Parida, Bhuvana Teja Lingipilli, Ramalingam Krishnan, Devendra Rao Podipireddy, Nethaji Muniraj

Abstract readReview
In one paragraph

Review in Pathogens (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed.

  1. Review
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  10. Article
  11. The plasma proteome and breast cancer risk.Breast cancer research : BCR · 2025
    Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Potential role of microbiota in ovarian cancer treatment.Archives of medical science : AMS · 2025
    Article
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Sathiyapriya ViswanathanDepartment of Biochemistry, ACS Medical College and Hospital, Chennai 600007, Tamil Nadu, India.ORCID 0000-0002-9067-4994
Sheetal ParidaDepartment of Oncology, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA.
Bhuvana Teja LingipilliGandhi Institute of Technology and Management (GITAM), Deemed University, Visakhapatnam 530045, Andhra Pradesh, India.
Ramalingam KrishnanDepartment of Biochemistry, Narayana Medical College, Nellore 524003, Andhra Pradesh, India.
Devendra Rao PodipireddyRangaraya Medical College, Dr. YSR University of Health Sciences, Kakinada 533001, Andhra Pradesh, India.
Nethaji MunirajCenter for Cancer and Immunology Research, Children's National Hospital, 111, Michigan Ave NW, Washington, DC 20010, USA.ORCID 0000-0002-3820-2148

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Breast cancer is the most common malignancy in women worldwide. The cause of cancer is multifactorial. An early diagnosis and the appropriate treatment of cancer can improve the chances of survival. Recent studies have shown that breast cancer is influenced by the microbiota. Different microbial signatures have been identified in the breast microbiota, which have different patterns depending on the stage and biological subgroups. The human digestive system contains approximately 100 trillion bacteria. The gut microbiota is an emerging field of research that is associated with specific biological processes in many diseases, including cardiovascular disease, obesity, diabetes, brain disease, rheumatoid arthritis, and cancer. In this review article, we discuss the impact of the microbiota on breast cancer, with a primary focus on the gut microbiota's regulation of the breast cancer microenvironment. Ultimately, updates on how immunotherapy can affect the breast cancer-based microbiome and further clinical trials on the breast and microbiome axis may be an important piece of the puzzle in better predicting breast cancer risk and prognosis.

Indexed as

biomarker and immunotherapybreast cancercancer therapeuticsdrug resistancemicrobiome

Identifiers

PMID36986390
PMCPMC10058520

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.