Evidence map›Paper›PMID 36986380›Full record

ArticlePathogens (Basel, Switzerland)2023

XENOFOOD-An Autoclaved Feed Supplement Containing Autoclavable Antimicrobial Peptides-Exerts Anticoccidial GI Activity, and Causes Bursa Enlargement, but Has No Detectable Harmful Effects in Broiler Cockerels despite In Vitro Detectable Cytotoxicity on LHM Cells.

András Fodor, Tibor Vellai, Claudia Hess, László Makrai, Károly Dublecz, László Pál, Andor Molnár, Michael G Klein, Eustachio Tarasco, Sándor Józsa and 2 more

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.0field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 4 countries.

András FodorDepartment of Genetics, Eötvös Loránd University, Pázmány P. Sétány 1C, H-1117 Budapest, Hungary.ORCID 0000-0003-3495-0154
Tibor VellaiDepartment of Genetics, Eötvös Loránd University, Pázmány P. Sétány 1C, H-1117 Budapest, Hungary.
Claudia HessClinic for Poultry and Fish Medicine, Department for Farm Animals and Veterinary Public Health, University of Veterinary Medicine (Vetmeduni Vienna), 1210 Vienna, Austria.ORCID 0000-0002-3535-5157
László MakraiDepartment of Microbiology and Infectious Diseases, University of Veterinary Medicine, H-1581 Budapest, Hungary.
Károly DubleczInstitute of Physiology and Nutrition, Georgikon Campus, Hungarian University of Agriculture and Life Sciences (MATE), Deák Ferenc utca 16, H-8360 Keszthely, Hungary.ORCID 0000-0001-6913-219X
László PálInstitute of Physiology and Nutrition, Georgikon Campus, Hungarian University of Agriculture and Life Sciences (MATE), Deák Ferenc utca 16, H-8360 Keszthely, Hungary.ORCID 0000-0001-9838-6703
Andor MolnárInstitute of Physiology and Nutrition, Georgikon Campus, Hungarian University of Agriculture and Life Sciences (MATE), Deák Ferenc utca 16, H-8360 Keszthely, Hungary.
Michael G KleinUSDA-ARS & Department of Entomology, The Ohio State University, 13416 Claremont Ave., Cleveland, OH 44130, USA.
Eustachio TarascoDepartment of Soil, Plant and Food Sciences, University of Bari "Aldo Moro", Via Amendola 165/A, 70126 Bari, Italy.ORCID 0000-0001-6310-186X
Sándor JózsaInstitute of Physiology and Nutrition, Georgikon Campus, Hungarian University of Agriculture and Life Sciences (MATE), Deák Ferenc utca 16, H-8360 Keszthely, Hungary.
Petra GanasClinic for Poultry and Fish Medicine, Department for Farm Animals and Veterinary Public Health, University of Veterinary Medicine (Vetmeduni Vienna), 1210 Vienna, Austria.
Michael HessClinic for Poultry and Fish Medicine, Department for Farm Animals and Veterinary Public Health, University of Veterinary Medicine (Vetmeduni Vienna), 1210 Vienna, Austria.ORCID 0000-0002-6991-0120
Magyar Agrár- és Élettudományi Egyetem · HUUniversity of Veterinary Medicine Vienna · ATEötvös Loránd University · HUThe Ohio State University · USUniversity of Bari Aldo Moro · ITUniversity of Veterinary Medicine · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Entomopathogenic bacteria are obligate symbionts of entomopathogenic nematode (EPN) species. These bacteria biosynthesize and release non-ribosomal-templated hybrid peptides (NR-AMPs), with strong, and large-spectral antimicrobial potential, capable of inactivating pathogens belonging to different prokaryote, and eukaryote taxa. The cell-free conditioned culture media (CFCM) of

Indexed as

alternative antibioticsanti-bacterialanti-coccidialanti-microbialanti-protist activityCFCM (cell-free conditioned media)Clostridium CFU—(colony forming unit)cytotoxicityEPB (entomo-pathogenic bacteria, Xenorhabdus, (X. budapestensis, X. szentirmaii, X. innexii), and Photorhabdus species)in situ (local) bioavailabilityMDRmultidrug resistanceNR-AMP (non-ribosomal-templated antimicrobial peptides)XENOFOOD

Identifiers

PMID36986380
PMCPMC10059668
OpenAlexW4324360804

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.