Evidence map›Paper›PMID 36986373›Full record

ArticlePathogens (Basel, Switzerland)2023

Pre-Vaccination Human Papillomavirus Genotypes and HPV16 Variants among Women Aged 25 Years or Less with Cervical Cancer.

Yasmin L Jayasinghe, Sepehr N Tabrizi, Matthew Stevens, Trishe Y-M Leong, Jan Pyman, Sonia R Grover, Suzanne M Garland, The Early-Onset Cervical Cancer Eocc Study Group

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pathogens (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Yasmin L JayasingheDepartment of Obstetrics and Gynaecology, Royal Women's Hospital, The University of Melbourne, Melbourne, VIC 3010, Australia.ORCID 0000-0001-5975-9378
Sepehr N TabriziDepartment of Obstetrics and Gynaecology, Royal Women's Hospital, The University of Melbourne, Melbourne, VIC 3010, Australia.
Matthew StevensThe Australian Genome Research Facility, Melbourne, VIC 3050, Australia.
Trishe Y-M LeongDepartment of Anatomical Pathology, St. Vincents Hospital, Melbourne, VIC 3000, Australia.
Jan PymanDepartment of Anatomical Pathology, Royal Women's Hospital, Melbourne, VIC 3010, Australia.
Sonia R GroverDepartment of Gynaecology, Royal Children's Hospital, Melbourne, VIC 3010, Australia.
Suzanne M GarlandDepartment of Obstetrics and Gynaecology, Royal Women's Hospital, The University of Melbourne, Melbourne, VIC 3010, Australia.
The Early-Onset Cervical Cancer Eocc Study Group
Royal Women's Hospital · AURoyal Children's Hospital · AUAGRF Ltd · AUSt Vincent's Hospital Melbourne · AU

Funding

Cancer Council Victoria PhD ScholarshipNational Health and Medical Research Council 568971Royal Australasian College of Physicians Novartis ScholarshipRoyal Australian and New Zealand College of Obstetricians and Gynaecologists PhD ScholarshipVictorian Cancer Agency Tumour Project Grant
6 · The paper itself

Abstract

backgroundIn 2007, Australia introduced a national human papillomavirus (HPV) vaccination program. In 2017, the onset of cervical screening changed from 18 to 25 years of age, utilising human papillomavirus (HPV) nucleic acid testing. The objective of the study is to describe the HPV genotypes and HPV16 variants in biopsies from women ≤ 25 years of age with cervical carcinoma (CC) (cases), compared with those aged >25 years (controls), in a pre-vaccination cohort.

methodsHPV genotyping of archival paraffin blocks (

resultsHPV16 was the commonest genotype in cases (54.5%, 12/22) and controls (66.7%, 46/69) (

conclusionsVirological factors may account for the differences in CCs observed in younger compared with older women. All CCs in young women in this study had preventable 9vHPV types, which is important messaging for health provider adherence to new cervical screening guidelines.

Indexed as

Asian American lineageAsian lineagecervical cancerE6350European variantgenotypingHPV16 variantsHPV vaccinehuman papillomavirusyoung women

Identifiers

PMID36986373
PMCPMC10051959
OpenAlexW4324143655

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.