Evidence map›Paper›PMID 36986327›Full record

ArticlePathogens (Basel, Switzerland)2023

Alexandre Robert, Emilie Talagrand-Reboul, Maria-Jose Figueras, Raymond Ruimy, Laurent Boyer, Brigitte Lamy

Open access · goldAbstract read
In one paragraph

Article in Pathogens (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Antimicrobial Effect of Diphenyl Ditelluride (PhTe)Indian journal of microbiology · 2024
    Article
  3. Interactions betweenFrontiers in microbiology · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Alexandre RobertLaboratoire C3M, Inserm U1065, Université Côte d'Azur, 06200 Nice, France.ORCID 0000-0003-1360-2513
Emilie Talagrand-ReboulLaboratoire de Bactériologie, Pole Biologie, CHRU de Strasbourg, UR7290, Université de Strasbourg, 67000 Strasbourg, France.
Maria-Jose FiguerasUnitat de Microbiologia, Departament de Ciènces Médiques Bàsiques, Facultat de Medicina i Ciències de la Salut, IISPV, Universitat Rovira i Virgili, 43201 Reus, Spain.
Raymond RuimyLaboratoire C3M, Inserm U1065, Université Côte d'Azur, 06200 Nice, France.
Laurent BoyerLaboratoire C3M, Inserm U1065, Université Côte d'Azur, 06200 Nice, France.ORCID 0000-0002-1375-1706
Brigitte LamyLaboratoire C3M, Inserm U1065, Université Côte d'Azur, 06200 Nice, France.
Inserm · FRHôpitaux Universitaires de Strasbourg · FRInstitut de Recerca Biomèdica Catalunya Sud · ES

Funding

Fondation pour la Recherche Médicale DEA20170839106
6 · The paper itself

Abstract

backgroundPolymicrobial infections are complex infections associated with worse outcomes compared to monomicrobial infections. We need simple, fast, and cost-effective animal models to assess their still poorly known pathogenesis.

methodsWe developed a

resultsIndividual strains killed more than 80% of the flies in 20 h. The course of infection could be altered with a microbial mix. The model could distinguish between the diverse effects (synergistic, antagonistic, and no difference) that resulted in a milder, more severe, or similar infection, depending on the paired strain considered. We then investigated the determinants of the effects. The effects were maintained in deficient fly lineages for the main signaling pathways (Toll deficient and IMD deficient), which suggests an active microbe/microbe/host interaction.

conclusionThese results indicate that the

Indexed as

AeromonasDrosophila melanogasterinfection modelmicrobial interferenceopportunistic pathogenpolymicrobial infection

Identifiers

PMID36986327
PMCPMC10055632
OpenAlexW4323043365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.