Evidence map›Paper›PMID 36986264›Full record

SynthesisNutrients2023

The Effect of Exercise Prescription on the Human Gut Microbiota and Comparison between Clinical and Apparently Healthy Populations: A Systematic Review.

Alexander N Boytar, Tina L Skinner, Ruby E Wallen, David G Jenkins, Marloes Dekker Nitert

Registry-linked trialAbstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06368713 (Exercise Improves Gastrointestinal Function in Peritoneal Dialysis Patients), which is not on this map. Cited by 44 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06368713 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Exercise Improves Gastrointestinal Function in Peritoneal Dialysis Patients: A Single Center Prospective Randomized Controlled Study

TypeinterventionalSponsorSichuan Academy of Medical SciencesRan2024 to 2025Enrolled132ConditionsPeritoneal Dialysis, Exercise, Gastrointestinal Function, Quality of LifeArmsExercise
3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  8. Review
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  19. Article
  20. Exercise benefits in metabolism on cardiovascular disease.Frontiers in cardiovascular medicine · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alexander N BoytarSchool of Human Movement and Nutrition Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
Tina L SkinnerSchool of Human Movement and Nutrition Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0002-5704-2741
Ruby E WallenSchool of Human Movement and Nutrition Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
David G JenkinsSchool of Human Movement and Nutrition Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
Marloes Dekker NitertSchool of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0002-1909-8920

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study systematically reviewed all human longitudinal exercise interventions that reported changes in the gut microbiota; frequency, intensity, duration and type of exercise were assessed to determine the influence of these variables on changes to the gut microbiota in both healthy individuals and clinical populations (PROPERO registration: CRD42022309854). Using PRISMA guidelines, trials analysing gut microbiota change with exercise interventions were included independent of trial randomisation, population, trial duration or analysis technique. Studies were excluded when microbiota abundance was not reported or when exercise was combined with other interventions. Twenty-eight trials were included, of which twelve involved healthy populations only and sixteen involved mixed or clinical-only populations. The findings show that participation in exercise of moderate to high-intensity for 30-90 min ≥3 times per week (or between 150-270 min per week) for ≥8 weeks is likely to produce changes in the gut microbiota. Exercise appears to be effective in modifying the gut microbiota in both clinical and healthy populations. A more robust methodology is needed in future studies to improve the certainty of the evidence.

Indexed as

Gastrointestinal MicrobiomeExerciseHealth StatusHumansPrescriptionsexercise durationexercise frequencyexercise intensitygut microbiotamicrobiomephysical activity

Identifiers

PMID36986264
PMCPMC10054511

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.