Evidence map›Paper›PMID 36986258›Full record

ArticleNutrients2023

Role of Dietary Defatted Rice Bran in the Modulation of Gut Microbiota in AOM/DSS-Induced Colitis-Associated Colorectal Cancer Rat Model.

Laleewan Tajasuwan, Aikkarach Kettawan, Thanaporn Rungruang, Kansuda Wunjuntuk, Pinidphon Prombutara

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Tanshinones fromActa biochimica et biophysica Sinica · 2026
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  5. Effect of Garambullo (International journal of molecular sciences · 2026
    Article
  6. Recent advances in novel targeting mechanisms for colorectal cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
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  8. Article
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  11. Review
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  17. Review
  18. Pomegranate (International journal of molecular sciences · 2023
    Review
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Laleewan TajasuwanGraduate Student in Doctor of Philosophy Program in Nutrition, Faculty of Medicine Ramathibodi Hospital and Institute of Nutrition, Mahidol University, Bangkok 10400, Thailand.
Aikkarach KettawanInstitute of Nutrition, Mahidol University, Nakhon Pathom 73170, Thailand.
Thanaporn RungruangDepartment of Anatomy, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand.
Kansuda WunjuntukDepartment of Home Economics, Faculty of Agriculture, Kasetsart University, Bangkok 10900, Thailand.ORCID 0000-0001-9403-3310
Pinidphon PrombutaraOMICS Sciences and Bioinformatics Center, Faculty of Science, Chulalongkorn University, Bangkok 10330, Thailand.
Mahidol University · THChulalongkorn University · THKasetsart University · THSiriraj Hospital · TH

Funding

Agricultural Research Development Agency (Public Organization) or "ARDA" PRP6405030310Thailand Research Fund (TRF) and the Researchers for Industries (RRI) Scheme PHD62I0006
6 · The paper itself

Abstract

Defatted rice bran (DRB) is a by-product of rice bran derived after the oil extraction. DRB contains several bioactive compounds, including dietary fiber and phytochemicals. The supplementation with DRB manifests chemopreventive effects in terms of anti-chronic inflammation, anti-cell proliferation, and anti-tumorigenesis in the azoxymethane (AOM) and dextran sodium sulfate (DSS)-induced colitis-associated colorectal cancer (CRC) model in rats. However, little is known about its effect on gut microbiota. Herein, we investigated the effect of DRB on gut microbiota and short chain fatty acid (SCFA) production, colonic goblet cell loss, and mucus layer thickness in the AOM/DSS-induced colitis-associated CRC rat model. The results suggested that DRB enhanced the production of beneficial bacteria (

Indexed as

ColitisColitis-Associated NeoplasmsGastrointestinal MicrobiomeOryzaAnimalsAzoxymethaneBacteriaBacteroidetesColonDextran SulfateDisease Models, AnimalMiceMice, Inbred C57BLRatsAzoxymethaneDextran Sulfatecolitis-associated colorectal cancerdefatted rice branfiber-degrading bacteriagoblet cell lossgut microbiotahealthhealth productmucus layer thicknessshort-chain fatty acid (SCFA)-producing bacteriashort-chain fatty acids (SCFAs)

Identifiers

PMID36986258
PMCPMC10052090
OpenAlexW4353073430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.