Evidence map›Paper›PMID 36986206›Full record

ArticleNutrients2023

Insulin, Testosterone, and Albumin in Term and Preterm Breast Milk, Donor Milk, and Infant Formula.

Réka A Vass, Edward F Bell, Robert D Roghair, Gabriella Kiss, Simone Funke, Szilvia Bokor, Dénes Molnár, Attila Miseta, József Bódis, Kálmán Kovács and 1 more

Open access · goldAbstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Réka A VassDepartment of Obstetrics and Gynecology, Medical School University of Pécs, 7624 Pécs, Hungary.ORCID 0000-0002-0436-4261
Edward F BellStead Family Department of Pediatrics, University of Iowa, Iowa City, IA 52242, USA.
Robert D RoghairStead Family Department of Pediatrics, University of Iowa, Iowa City, IA 52242, USA.ORCID 0000-0002-0321-582X
Gabriella KissDepartment of Laboratory Medicine, Medical School University of Pécs, 7624 Pécs, Hungary.
Simone FunkeDepartment of Obstetrics and Gynecology, Medical School University of Pécs, 7624 Pécs, Hungary.
Szilvia BokorMTA-PTE Human Reproduction Scientific Research Group, University of Pécs, 7624 Pécs, Hungary.
Dénes MolnárMTA-PTE Human Reproduction Scientific Research Group, University of Pécs, 7624 Pécs, Hungary.ORCID 0000-0002-3675-7019
Attila MisetaDepartment of Laboratory Medicine, Medical School University of Pécs, 7624 Pécs, Hungary.
József BódisDepartment of Obstetrics and Gynecology, Medical School University of Pécs, 7624 Pécs, Hungary.
Kálmán KovácsDepartment of Obstetrics and Gynecology, Medical School University of Pécs, 7624 Pécs, Hungary.
Tibor ErtlDepartment of Obstetrics and Gynecology, Medical School University of Pécs, 7624 Pécs, Hungary.
University of Pecs · HUUniversity of Iowa · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundInfants have three options for feeding: their own mother's breast milk, donor milk, or infant formula. Insulin, testosterone, total protein, and albumin levels were measured in breast milk samples from the first 6 months of lactation, in donor milk samples, and in different infant formulas.

methodsMothers who gave birth to term (

resultsDuring the first 2 months of lactation, the concentration of insulin was lower (-27.4%) while the testosterone concentration was higher (+20.8%) compared to the period between the 3rd and 6th months only in the preterm breast milk samples. The infant formulas examined did not contain insulin or testosterone. Holder pasteurization (HoP) did not influence the level of testosterone in human milk, although HoP decreased the insulin (-53.6%) and albumin (-38.6%) concentrations.

conclusionsDiet impacts the hormone intake of infants, underlining the importance of breastfeeding and the possible supplementation of formula-fed infants.

Indexed as

Infant FormulaMilk, HumanAlbuminsBreast FeedingFemaleHumansInfantInfant, NewbornInfant Nutritional Physiological PhenomenaInfant, PrematureInsulinTestosteroneAlbuminsInsulinTestosteronealbumin/protein ratiodonor milkholder pasteurizationinfant formulainsulinpreterm milkterm milktestosterone

Identifiers

PMID36986206
PMCPMC10051190
OpenAlexW4327977644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.