Evidence map›Paper›PMID 36986037›Full record

ArticleNutrients2023

Identification and Selection of Prospective Probiotics for Enhancing Gastrointestinal Digestion: Application in Pharmaceutical Preparations and Dietary Supplements.

Claudia Cappello, Ali Zein Alabiden Tlais, Marta Acin-Albiac, Wilson José Fernandes Lemos Junior, Daniela Pinto, Pasquale Filannino, Fabio Rinaldi, Marco Gobbetti, Raffaella Di Cagno

Abstract read
In one paragraph

Article in Nutrients, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Claudia CappelloFaculty of Science and Technology, Free University of Bolzano, 39100 Bolzano, Italy.
Ali Zein Alabiden TlaisFaculty of Science and Technology, Free University of Bolzano, 39100 Bolzano, Italy.
Marta Acin-AlbiacFaculty of Science and Technology, Free University of Bolzano, 39100 Bolzano, Italy.
Wilson José Fernandes Lemos JuniorFaculty of Science and Technology, Free University of Bolzano, 39100 Bolzano, Italy.
Daniela PintoHuman Microbiome Advanced Project, Research & Development, 20129 Milano, Italy.ORCID 0000-0001-8107-106X
Pasquale FilanninoDepartment of Soil, Plant and Food Science, University of Bari Aldo Moro, 70121 Bari, Italy.ORCID 0000-0002-1235-5138
Fabio RinaldiHuman Microbiome Advanced Project, Research & Development, 20129 Milano, Italy.
Marco GobbettiFaculty of Science and Technology, Free University of Bolzano, 39100 Bolzano, Italy.
Raffaella Di CagnoFaculty of Science and Technology, Free University of Bolzano, 39100 Bolzano, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our study investigated the effectiveness of 446 strains of lactic acid bacteria (LAB) belonging to different species and isolated from diverse sources (food, human, and animal) as potential probiotic candidates, with the perspective of producing dietary supplements or pharmacological formulations suitable for enhancing gastrointestinal digestion. The survival capability of all the isolates under harsh gastrointestinal tract conditions was evaluated, in which only 44 strains, named high-resistant, were selected for further food digestibility investigations. All 44 strains hydrolyzed raffinose and exhibited amino and iminopeptidase activities but at various extents, confirming species- and strain-specificity. After partial in vitro digestion mimicking oral and gastric digestive phases, food matrices were incubated with single strains for 24 h. Fermented partially digested matrices provided additional functional properties for some investigated strains by releasing peptides and increasing the release of highly bio-accessible free phenolic compounds. A scoring procedure was proposed as an effective tool to reduce data complexity and quantitively characterize the probiotic potential of each LAB strain, which could be more useful in the selection procedure of powerful probiotics.

Indexed as

LactobacillalesProbioticsAnimalsDigestionHumansPharmaceutical PreparationsProspective StudiesPharmaceutical Preparationsanti-nutritional compoundsdigestibilityfood functionalitylactic acid bacteriascoring approach

Identifiers

PMID36986037
PMCPMC10053534

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.