Evidence map›Paper›PMID 36985807›Full record

ArticleMolecules (Basel, Switzerland)2023

Evaluation of the Antihypertensive Activity of Eggplant Acetylcholine and γ-Aminobutyric Acid in Spontaneously Hypertensive Rats.

Wenhao Wang, Shohei Yamaguchi, Masahiro Koyama, Kozo Nakamura

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Wenhao WangDepartment of Science and Technology, Graduate School of Medicine, Science and Technology, Shinshu University, 8304 Minamiminowa, Nagano 399-4598, Japan.ORCID 0000-0002-6499-9779
Shohei YamaguchiWellnas Co., Ltd., 1-28-5 Koenjiminami, Suginami-Ku, Tokyo 166-0003, Japan.
Masahiro KoyamaWellnas Co., Ltd., 1-28-5 Koenjiminami, Suginami-Ku, Tokyo 166-0003, Japan.
Kozo NakamuraDepartment of Science and Technology, Graduate School of Medicine, Science and Technology, Shinshu University, 8304 Minamiminowa, Nagano 399-4598, Japan.
Shinshu University · JP

Funding

The NARO Bio-oriented Technology Research Advancement Institution's Special Scheme Project on Vitalizing Management Entities of Agriculture, Forestry, and Fisheries provided funding for this study 16932813
6 · The paper itself

Abstract

Daily consumption of eggplant powder containing 2.3 mg acetylcholine (ACh) is known to alleviate hypertension and improve mental status. However, eggplant powder used in clinical trials also contains the antihypertensive compound γ-aminobutyric acid (GABA). Although our previous study indicated that the main antihypertensive compound in eggplant is ACh, given that GABA amounts in eggplant do not reach the effective dosage, the effects of GABA on the antihypertensive effect of eggplant remain unclear. It is necessary to establish whether there is a synergistic effect between GABA and ACh and whether GABA in eggplant exerts antihypertensive effects. Consequently, here we sought to evaluate the effects of GABA on the antihypertensive effects of eggplant. We used a probability sum (

Indexed as

HypotensionSolanum melongenaAcetylcholineAnimalsAntihypertensive AgentsBlood Pressuregamma-Aminobutyric AcidPowdersRatsRats, Inbred SHRAcetylcholineAntihypertensive Agentsgamma-Aminobutyric AcidPowdersacetylcholineeggplantfunctional foodhypertensionspontaneously hypertensive ratγ-aminobutyric acid

Identifiers

PMID36985807
PMCPMC10051710
OpenAlexW4353073404

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.