Evidence map›Paper›PMID 36985792›Full record

ArticleMolecules (Basel, Switzerland)2023

Assessment of Lipophilicity Parameters of Antimicrobial and Immunosuppressive Compounds.

Dawid Wardecki, Małgorzata Dołowy, Katarzyna Bober-Majnusz

Abstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Modeling of Effectiveness ofMolecules (Basel, Switzerland) · 2024
    Article
  11. Unveiling the Potential ofPharmaceuticals (Basel, Switzerland) · 2024
    Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Dawid WardeckiFaculty of Pharmaceutical Sciences in Sosnowiec, Doctoral School, Medical University of Silesia in Katowice, 41-200 Sosnowiec, Poland.ORCID 0000-0002-2852-1647
Małgorzata DołowyDepartment of Analytical Chemistry, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, 41-200 Sosnowiec, Poland.ORCID 0000-0003-0425-5468
Katarzyna Bober-MajnuszDepartment of Analytical Chemistry, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, 41-200 Sosnowiec, Poland.ORCID 0000-0001-5150-0396

Funding

Medical University of Silesia PCN-1-009/N/2/F
6 · The paper itself

Abstract

Lipophilicity in addition to the solubility, acid-base character and stability is one of the most important physicochemical parameters of a compound required to assess the ADMET properties (absorption, distribution, metabolism, excretion and toxicity) of a bioactive molecule. Therefore, the subject of this work was to determine the lipophilicity parameters of selected antimicrobial and immunosuppressive compounds such as delafloxacin, linezolid, sutezolid, ceftazidime, everolimus and zotarolimus using thin-layer chromatography in reversed phase system (RP-TLC). The chromatographic parameters of lipophilicity (R

Indexed as

Anti-Infective AgentsChromatography, Reverse-PhaseChromatography, Thin LayerHydrophobic and Hydrophilic InteractionsImmunosuppressive AgentsSolubilityAnti-Infective AgentsImmunosuppressive Agentsantimicrobial drugsbioactive moleculeschromatographyimmunosuppressive compoundslipophilicityTLC

Identifiers

PMID36985792
PMCPMC10059999

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.