Evidence map›Paper›PMID 36985724›Full record

ArticleMolecules (Basel, Switzerland)2023

Glycoprotein In Vitro N-Glycan Processing Using Enzymes Expressed in

Libo Zhang, Yanhong Li, Riyao Li, Xiaohong Yang, Zimin Zheng, Jingxin Fu, Hai Yu, Xi Chen

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
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  11. Chemoenzymatic Synthesis ofTetrahedron · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Libo ZhangDepartment of Chemistry, University of California, Davis, CA 95616, USA.
Yanhong LiDepartment of Chemistry, University of California, Davis, CA 95616, USA.
Riyao LiDepartment of Chemistry, University of California, Davis, CA 95616, USA.
Xiaohong YangDepartment of Chemistry, University of California, Davis, CA 95616, USA.
Zimin ZhengDepartment of Chemistry, University of California, Davis, CA 95616, USA.
Jingxin FuDepartment of Chemistry, University of California, Davis, CA 95616, USA.
Hai YuDepartment of Chemistry, University of California, Davis, CA 95616, USA.
Xi ChenDepartment of Chemistry, University of California, Davis, CA 95616, USA.ORCID 0000-0002-3160-614X
University of California, Davis · US

Funding

Acquisition of a Q-Exactive Plus Mass SpectrometerS10OD025271 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI JEWELL, WILLIAM T · 2019 to 2019
$486k
NIH HHS S10OD018913NIH HHS S10 OD025271NIH HHS S10OD025271
6 · The paper itself

Abstract

Protein N-glycosylation is a common post-translational modification that plays significant roles on the structure, property, and function of glycoproteins. Due to N-glycan heterogeneity of naturally occurring glycoproteins, the functions of specific N-glycans on a particular glycoprotein are not always clear. Glycoprotein in vitro N-glycan engineering using purified recombinant enzymes is an attractive strategy to produce glycoproteins with homogeneous N-glycoforms to elucidate the specific functions of N-glycans and develop better glycoprotein therapeutics. Toward this goal, we have successfully expressed in

Indexed as

Escherichia coliGlycoproteinsGlycoside HydrolasesGlycosylationHumansPolysaccharidesGlycoproteinsGlycoside HydrolasesPolysaccharidesE. coli expressionglycan engineeringglycoproteinglycosyltransferasemannosidaseN-glycan

Identifiers

PMID36985724
PMCPMC10051842
OpenAlexW4327973125

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.