ReviewMolecules (Basel, Switzerland)2023
Sharpless Asymmetric Dihydroxylation: An Impressive Gadget for the Synthesis of Natural Products: A Review.
Review in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Molecular rearrangements as powerful tools in diversity-oriented natural products synthesis: a review.RSC advances · 2026Review
- Hypervalent iodine reagents in organic synthesis: a review of methodology developments and synthetic applications.RSC advances · 2026Review
- Total Synthesis and Structural Revision of Bonnevillamides B and C.Organic letters · 2026Article
- A review on the sulfur ylide-mediated Corey-Chaykovsky reaction: a powerful approach to natural product synthesis.RSC advances · 2025Review
- Data-Driven Prediction of Enantioselectivity for the Sharpless Asymmetric Dihydroxylation: Model Development and Experimental Validation.ACS central science · 2025Article
- 7-Methoxybenzofuran-triazole tetheredRSC advances · 2025Article
- Total Syntheses of Deuterated Drugs: A Comprehensive Review.Topics in current chemistry (Cham) · 2025Review
- The Duality of Dioxolanyl Radicals towards C-C Bond Construction.Synlett : accounts and rapid communications in synthetic organic chemistry · 2025Article
- Unified Hydrogen Atom Transfer Approach To Construct Vicinal Functionality.Organic letters · 2025Article
- Mechanistic Investigations into the Olefination of Oximes and Hydrazones Support Intermediate Ruthenium Nitrides.Journal of the American Chemical Society · 2025Article
- Exploring the Synthetic Potential of Horner-Wadsworth-Emmons Reaction Toward the Synthesis of Polyketide Based Natural Products: A Review.Topics in current chemistry (Cham) · 2025Review
- Corey-Fuchs reaction enabled synthesis of natural products: a review.RSC advances · 2025Review
- Cyclic Osmate Esters from 1,2- and 1,3-Diols and α-Hydroxy Acids for X-ray Analysis.The Journal of organic chemistry · 2025Article
- Mukaiyama aldol reaction: an effective asymmetric approach to access chiral natural products and their derivatives/analogues.RSC advances · 2023Review
- Asymmetric Synthesis of Four Stereoisomers of 2,2-Dimethyl-3-hydroxy-4-(1'-angeloyloxy)-6-acetylchromane fromACS omega · 2023Article
- Effects of Gold Nanoparticles Phytoreduced with Rutin in an Early Rat Model of Diabetic Retinopathy and Cataracts.Metabolites · 2023Article
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Authors and funding
9 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Sharpless asymmetric dihydroxylation is an important reaction in the enantioselective synthesis of chiral vicinal diols that involves the treatment of alkene with osmium tetroxide along with optically active quinine ligand. Sharpless introduced this methodology after considering the importance of enantioselectivity in the total synthesis of medicinally important compounds. Vicinal diols, produced as a result of this reaction, act as intermediates in the synthesis of different naturally occurring compounds. Hence, Sharpless asymmetric dihydroxylation plays an important role in synthetic organic chemistry due to its undeniable contribution to the synthesis of biologically active organic compounds. This review emphasizes the significance of Sharpless asymmetric dihydroxylation in the total synthesis of various natural products, published since 2020.
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