Evidence map›Paper›PMID 36985587›Full record

ArticleMolecules (Basel, Switzerland)2023

Design, Synthesis, In Silico and POM Studies for the Identification of the Pharmacophore Sites of Benzylidene Derivatives.

Mohammad I Hosen, Yousef E Mukhrish, Ahmed Hussain Jawhari, Ismail Celik, Meryem Erol, Emad M Abdallah, Mohammed Al-Ghorbani, Mohammed Baashen, Faisal A Almalki, Hamid Laaroussi and 2 more

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 8 institutions in 4 countries.

Mohammad I HosenLaboratory of Carbohydrate and Nucleoside Chemistry (LCNC), Department of Chemistry, Faculty of Science, University of Chittagong, Chittagong 4331, Bangladesh.
Yousef E MukhrishDepartment of Chemistry, Faculty of Science, Jazan University, Jazan 45142, Saudi Arabia.ORCID 0000-0001-6268-0775
Ahmed Hussain JawhariDepartment of Chemistry, Faculty of Science, Jazan University, Jazan 45142, Saudi Arabia.ORCID 0000-0002-8444-8982
Ismail CelikDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Erciyes University, Kayseri 38280, Turkey.ORCID 0000-0002-8146-1663
Meryem ErolDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Erciyes University, Kayseri 38280, Turkey.ORCID 0000-0001-5676-098X
Emad M AbdallahDepartment of Science Laboratories, College of Science and Arts, Qassim University, Ar Rass 51921, Saudi Arabia.ORCID 0000-0003-0549-249X
Mohammed Al-GhorbaniDepartment of Chemistry, Faculty of Science and Arts, Ulla, Taibah University, Medina 41477, Saudi Arabia.ORCID 0000-0002-9079-5788
Mohammed BaashenDepartment of Chemistry, Science and Humanities College, Shaqra University, Ad-Dawadmi 11911, Saudi Arabia.ORCID 0000-0003-0297-9489
Faisal A AlmalkiDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Umm Al-Qura University, Makkah 21955, Saudi Arabia.
Hamid LaaroussiLaboratory of Applied Chemistry & Environment, Faculty of Sciences, Mohammed Premier University, Oujda 60000, Morocco.ORCID 0000-0002-8502-6239
Taibi Ben HaddaDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Umm Al-Qura University, Makkah 21955, Saudi Arabia.ORCID 0000-0002-5633-6203
Sarkar M A KawsarLaboratory of Carbohydrate and Nucleoside Chemistry (LCNC), Department of Chemistry, Faculty of Science, University of Chittagong, Chittagong 4331, Bangladesh.ORCID 0000-0001-7964-9117
Erciyes University · TRJazan University · SAUmm al-Qura University · SAUniversity of Chittagong · BDMohamed I University · MAQassim University · SAShaqra University · SATaibah University · SA

Funding

University of Chittagong 2022-2023
6 · The paper itself

Abstract

Due to the uneven distribution of glycosidase enzyme expression across bacteria and fungi, glycoside derivatives of antimicrobial compounds provide prospective and promising antimicrobial materials. Therefore, herein, we report the synthesis and characterization of six novel methyl 4,6-

Indexed as

Antifungal AgentsAnti-Infective AgentsAnti-Bacterial AgentsBacteriaBenzylidene CompoundsHumansMicrobial Sensitivity TestsMolecular Docking SimulationMolecular StructurePharmacophoreStructure-Activity RelationshipAnti-Bacterial AgentsAntifungal AgentsAnti-Infective AgentsBenzylidene Compoundsantimicrobialidentification of pharmacophore sitesmethyl 4,6-O-benzylidene-α-d-glucopyranosidemolecular dynamicsPASS predictionPOM theory

Identifiers

PMID36985587
PMCPMC10053039
OpenAlexW4324146415

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.