Evidence map›Paper›PMID 36985455›Full record

ArticleMolecules (Basel, Switzerland)2023

Vanadium-Containing Anionic Chelate for Spectrophotometric Determination of Hydroxyzine Hydrochloride in Pharmaceuticals.

Gergana Kirilova Kirova, Zdravka Yancheva Velkova, Vassil Borisov Delchev, Kiril Blazhev Gavazov

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In one paragraph

Article in Molecules (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gergana Kirilova KirovaDepartment of Chemical Sciences, Faculty of Pharmacy, Medical University of Plovdiv, 120 Buxton Bros Str., 4004 Plovdiv, Bulgaria.
Zdravka Yancheva VelkovaDepartment of Chemical Sciences, Faculty of Pharmacy, Medical University of Plovdiv, 120 Buxton Bros Str., 4004 Plovdiv, Bulgaria.
Vassil Borisov DelchevFaculty of Chemistry, University of Plovdiv 'Paisii Hilendarskii', 24 Tsar Assen St., 4000 Plovdiv, Bulgaria.
Kiril Blazhev GavazovDepartment of Chemical Sciences, Faculty of Pharmacy, Medical University of Plovdiv, 120 Buxton Bros Str., 4004 Plovdiv, Bulgaria.ORCID 0000-0002-1360-8977

Funding

National Centre for High-performance and Distributed Computing through grant No D01-168/28.07.2022 D01-168/28.07.2022
6 · The paper itself

Abstract

Four azo dyes known to form anionic complexes with V(V) were investigated as potential liquid-liquid extraction-spectrophotometric reagents for the antihistamine medication hydroxyzine hydrochloride (HZH). A stable ion-association complex suitable for analytical purposes was obtained with 6-hexyl-4-(2-thiazolylazo)resorcinol (HTAR). The molar absorption coefficient, limit of detection, linear working range, and relative standard deviation in the analysis of real pharmaceutical samples (tablets and syrup) were 3.50 × 10

Indexed as

HydroxyzineVanadiumIndicators and ReagentsPharmaceutical PreparationsSpectrophotometryHydroxyzineIndicators and ReagentsPharmaceutical PreparationsVanadium6-hexyl-4-(2-thiazolylazo)resorcinolDFT calculationshydroxyzineion associationliquid–liquid extractionpharmaceutical dosage formsspectrophotometric determinationvanadium(V)

Identifiers

PMID36985455
PMCPMC10051179

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.