Evidence map›Paper›PMID 36985367›Full record

ArticleMicroorganisms2023

Mucosa-Associated

Shukai Zhan, Caiguang Liu, Jixin Meng, Ren Mao, Tong Tu, Jianming Lin, Minhu Chen, Zhirong Zeng, Xiaojun Zhuang

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

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  13. Intestinal strictures in Crohn's disease: An update from 2023.United European gastroenterology journal · 2024
    Review
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Shukai ZhanDepartment of Gastroenterology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Caiguang LiuDepartment of Gastroenterology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.ORCID 0000-0003-4876-7000
Jixin MengDepartment of Radiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Ren MaoDepartment of Gastroenterology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Tong TuDepartment of Gastroenterology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Jianming LinDepartment of Gastroenterology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Minhu ChenDepartment of Gastroenterology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Zhirong ZengDepartment of Gastroenterology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Xiaojun ZhuangDepartment of Gastroenterology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Sun Yat-sen University · CN

Funding

China Postdoctoral Science Foundation Funding Agency 2021M703750Guangdong Basic and Applied Basic Research Foundation 2020A1515111087National Natural Science Foundation of China 82100576, 82200605, 81970483, 82170537 and 82222010Young S&T Talent Training Program of Guangdong Provincial Association for S&T SKXRC202202
6 · The paper itself

Abstract

Intestinal stricture remains one of the most intractable complications in Crohn's disease (CD), and the involved mechanisms are poorly understood. Accumulating evidence suggests that the gut microbiota contributes to the pathogenesis of intestinal fibrosis. In this study, we investigated specific mucosa-associated microbiota related to intestinal strictures and their role in predicting postoperative disease course. Twenty CD patients who had undergone operative treatments were enrolled and followed up. Intestinal mucosa and full-thickness sections from stenotic and non-stenotic sites were sterilely collected. DNA extraction and bacterial 16s rRNA gene sequencing were conducted. Radiological and histological evaluations were performed to assess fibrosis. Microbial alpha diversity was significantly decreased in stenotic sites (

Indexed as

Crohn’s diseaseintestinal fibrosisintestinal strictureOscillospirapost-operative recurrence

Identifiers

PMID36985367
PMCPMC10055919
OpenAlexW4327948838

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.