Evidence map›Paper›PMID 36985358›Full record

ReviewMicroorganisms2023

Iron Status and Supplementation during Tuberculosis.

Arista Nienaber, Mary A Uyoga, Robin C Dolman-Macleod, Linda Malan

Open access · goldAbstract readReview
In one paragraph

Review in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Hematochemical hallmarks as markers of pulmonary TB severity: A multicenter cross-sectional study.Journal of clinical tuberculosis and other mycobacterial diseases · 2025
    Article
  8. Article
  9. Review
  10. Role of Divalent Cations in Infections in Host-Pathogen Interaction.International journal of molecular sciences · 2024
    Review
  11. Article
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Arista NienaberCentre of Excellence for Nutrition, North-West University, Potchefstroom 2531, South Africa.ORCID 0000-0002-1013-6740
Mary A UyogaCentre of Excellence for Nutrition, North-West University, Potchefstroom 2531, South Africa.
Robin C Dolman-MacleodCentre of Excellence for Nutrition, North-West University, Potchefstroom 2531, South Africa.ORCID 0000-0003-4042-6228
Linda MalanCentre of Excellence for Nutrition, North-West University, Potchefstroom 2531, South Africa.
North-West University · ZA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tuberculosis (TB) is characterised by chronic non-resolving inflammation. The effects of the host immune and inflammatory response to reduce iron acquisition by the bacteria, together with other contributing factors, predispose TB patients to anaemia of infection and iron deficiency anaemia (IDA). The presence of anaemia in TB patients has been linked to poor clinical outcomes. However, due to the reliance of the bacteria on iron, the management of anaemia in TB is complicated, and anaemia of infection is likely to resolve with correct TB drug treatment. On the other hand, IDA may require iron supplementation. This review aims to describe iron metabolism in TB and how this contributes to the development of iron deficiency and anaemia. Additionally, we summarise the evidence on the association between iron status and clinical outcomes as well as the available preclinical and clinical trials on iron supplementation in TB.

Indexed as

anaemia of infectionironiron deficiency anaemiatuberculosis

Identifiers

PMID36985358
PMCPMC10055784
OpenAlexW4327948920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.