Evidence map›Paper›PMID 36985255›Full record

ArticleMicroorganisms2023

Water-Soluble Fullerene C

Ekaterina O Sinegubova, Olga A Kraevaya, Aleksandrina S Volobueva, Alexander V Zhilenkov, Alexander F Shestakov, Sergey V Baykov, Pavel A Troshin, Vladimir V Zarubaev

Abstract read
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Fullerene Gallium Phosphonate Shows Antimycobacterial Effect AgainstInternational journal of molecular sciences · 2025
    Article
  4. Article
  5. Article
  6. Highly aqueously stable CSmart medicine · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ekaterina O SinegubovaSaint Petersburg Pasteur Institute, 14 Ulitsa Mira, 197101 St. Petersburg, Russia.ORCID 0000-0001-9490-2280
Olga A KraevayaFederal Research Center for Problems of Chemical Physics and Medicinal Chemistry RAS, 1 Prospekt Akademika Semenova, 142432 Chernogolovka, Russia.
Aleksandrina S VolobuevaSaint Petersburg Pasteur Institute, 14 Ulitsa Mira, 197101 St. Petersburg, Russia.
Alexander V ZhilenkovFederal Research Center for Problems of Chemical Physics and Medicinal Chemistry RAS, 1 Prospekt Akademika Semenova, 142432 Chernogolovka, Russia.
Alexander F ShestakovFederal Research Center for Problems of Chemical Physics and Medicinal Chemistry RAS, 1 Prospekt Akademika Semenova, 142432 Chernogolovka, Russia.
Sergey V BaykovInstitute of Chemistry, Saint Petersburg State University, 7/9 Universitetskaya Nab., 199034 St. Petersburg, Russia.
Pavel A TroshinFederal Research Center for Problems of Chemical Physics and Medicinal Chemistry RAS, 1 Prospekt Akademika Semenova, 142432 Chernogolovka, Russia.ORCID 0000-0001-9957-4140
Vladimir V ZarubaevSaint Petersburg Pasteur Institute, 14 Ulitsa Mira, 197101 St. Petersburg, Russia.ORCID 0000-0002-5224-3771

Funding

Russian Science Foundation 19-13-00411-P
6 · The paper itself

Abstract

The influenza virus genome features a very high mutation rate leading to the rapid selection of drug-resistant strains. Due to the emergence of drug-resistant strains, there is a need for the further development of new potent antivirals against influenza with a broad activity spectrum. Thus, the search for a novel, effective broad-spectrum antiviral agent is a top priority of medical science and healthcare systems. In this paper, derivatives based on fullerenes with broad virus inhibiting activities in vitro against a panel of influenza viruses were described. The antiviral properties of water-soluble fullerene derivatives were studied. It was demonstrated that the library of compounds based on fullerenes has cytoprotective activity. Maximum virus-inhibiting activity and minimum toxicity were found with compound

Indexed as

antiviral agentfullerenehemagglutinininfluenza virus

Identifiers

PMID36985255
PMCPMC10053623

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.