Evidence map›Paper›PMID 36985232›Full record

ArticleMicroorganisms2023

Serum-Derived Bovine Immunoglobulin Stimulates SCFA Production by Specific Microbes in the Ex Vivo SIFR

Pieter Van den Abbeele, Christopher Detzel, Alexis Rose, Stef Deyaert, Aurélien Baudot, Christopher Warner

Open access · goldAbstract read
In one paragraph

Article in Microorganisms, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.5field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  3. Nutrients · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pieter Van den AbbeeleCryptobiotix SA, Technologiepark-Zwijnaarde 82, 9052 Ghent, Belgium.
Christopher DetzelProliant Health & Biologicals, LLC., Des Moines, IA 50021, USA.
Alexis RoseProliant Health & Biologicals, LLC., Des Moines, IA 50021, USA.
Stef DeyaertCryptobiotix SA, Technologiepark-Zwijnaarde 82, 9052 Ghent, Belgium.
Aurélien BaudotCryptobiotix SA, Technologiepark-Zwijnaarde 82, 9052 Ghent, Belgium.
Christopher WarnerProliant Health & Biologicals, LLC., Des Moines, IA 50021, USA.ORCID 0000-0003-4472-7503

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Serum-derived bovine immunoglobulins (SBI) exert health benefits mediated by their ability to bind microbial components, thereby preventing translocation and subsequent inflammation. While in vivo studies have shown that a fraction of SBI also reaches the colon, little is known about the impact of SBI on the dense colonic microbiota that has great potential to impact human health. This study, therefore, investigated the impact of three bovine plasma protein fractions (SBI, bovine plasma (BP) and albumin-enriched bovine plasma (ABP)) on the gut microbiota of six human adults using the novel ex vivo SIFR

Indexed as

dialysisex vivogut microbiotainterpersonal variationprebioticprotein fermentationserum-derived bovine immunoglobulin/protein isolate (SBI)SIFR® technology

Identifiers

PMID36985232
PMCPMC10053870
OpenAlexW4323313115

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.