Evidence map›Paper›PMID 36984980›Full record

ArticleMicromachines2023

Photoacoustic Flow Cytometry Using Functionalized Microspheres for Selective Detection of Bacteria.

Robert H Edgar, Anie-Pier Samson, Tori Kocsis, John A Viator

Open access · goldAbstract read
In one paragraph

Article in Micromachines, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Robert H EdgarDepartment of Bioengineering, University of Pittsburgh, Pittsburgh, PA 15260, USA.ORCID 0000-0002-3906-1930
Anie-Pier SamsonDepartment of Engineering, Duquesne University, Pittsburgh, PA 15282, USA.
Tori KocsisDepartment of Engineering, Duquesne University, Pittsburgh, PA 15282, USA.
John A ViatorDepartment of Engineering, Duquesne University, Pittsburgh, PA 15282, USA.
Duquesne University · USUniversity of Pittsburgh · US

Funding

National Institute of Health 1R01CA161367-01
6 · The paper itself

Abstract

Photoacoustic flow cytometry is a method to detect rare analytes in fluids. We developed photoacoustic flow cytometry to detect pathological cells in body fluids, such as circulating tumor cells or bacteria in blood. In order to induce specific optical absorption in bacteria, we use modified bacteriophage that precisely target bacterial species or subspecies for rapid identification. In order to reduce detection variability and to halt the lytic lifescycle that results in lysis of the bacteria, we attached dyed latex microspheres to the tail fibers of bacteriophage that retained the bacterial recognition binding sites. We tested these microsphere complexes using

Indexed as

acousticbiosensingoptoacoustics

Identifiers

PMID36984980
PMCPMC10057399
OpenAlexW4322619965

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.