Evidence map›Paper›PMID 36984859›Full record

ArticleMetabolites2023

Blackberry-Loaded AgNPs Attenuate Hepatic Ischemia/Reperfusion Injury via PI3K/Akt/mTOR Pathway.

Ahmed M Fathi, Shaimaa Waz, Eman Alaaeldin, Nisreen D M Toni, Azza A K El-Sheikh, Ahmed M Sayed, Usama Ramadan Abdelmohsen, Maiiada H Nazmy

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Ahmed M FathiDepartment of Biochemistry, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.ORCID 0000-0002-1291-1413
Shaimaa WazDepartment of Biochemistry, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.ORCID 0000-0002-1665-4864
Eman AlaaeldinDepartment of Pharmaceutics, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.
Nisreen D M ToniDepartment of Pathology, Faculty of Medicine, Minia University, Minia 61519, Egypt.
Azza A K El-SheikhBasic Health Sciences Department, College of Medicine, Princess Nourah Bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia.ORCID 0000-0003-3726-0386
Ahmed M SayedDepartment of Pharmacognosy, Faculty of Pharmacy, Nahda University, Beni-Suef 62513, Egypt.ORCID 0000-0002-1442-183X
Usama Ramadan AbdelmohsenDepartment of Pharmacognosy, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.ORCID 0000-0002-1014-6922
Maiiada H NazmyDepartment of Biochemistry, Faculty of Pharmacy, Minia University, Minia 61519, Egypt.ORCID 0000-0002-5537-3432
Minia University · EGDeraya UniversityNahda University · EGPrincess Nourah bint Abdulrahman University · SA

Funding

Princess Nourah bint Abdulrahman University Researchers Supporting Project number (PNURSP2023R91), Princess Nourah bint Abdulrahman University, Riyadh, Saudi Arabia. PNURSP2023R91
6 · The paper itself

Abstract

Liver ischemia-reperfusion injury (IRI) is a pathophysiological insult that often occurs during liver surgery. Blackberry leaves are known for their anti-inflammatory and antioxidant activities.

aimsTo achieve site-specific delivery of blackberry leaves extract (

methodsIRI was induced in male Wister rats. Liver injury, hepatic histology, oxidative stress markers, hepatic expression of apoptosis-related proteins were evaluated. Non-targeted metabolomics for chemical characterization of blackberry leaves extract was performed. KEY

findingsPre-treatment with SIGNIFICANCE:

Indexed as

AgNPsblackberrycaspase-3cell apoptosisliver ischemia-reperfusion injurymetabolomicsPI3K/Akt/mTOR

Identifiers

PMID36984859
PMCPMC10051224
OpenAlexW4324097088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.